CA 125 Levels in Treating Patients With Relapsed Advanced Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer Who Are Receiving Tamoxifen
NCT00305838 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2013-08-12
Summary
RATIONALE: Estrogen may cause the growth of ovarian cancer cells. Hormone therapy using tamoxifen may fight ovarian cancer by blocking the use of estrogen by the tumor cells. Measuring CA 125 levels may help doctors predict a patient's response to tamoxifen and help plan the best treatment.
PURPOSE: This phase II trial is studying CA 125 levels in treating patients with relapsed advanced ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who are receiving tamoxifen.
Conditions
- Fallopian Tube Cancer
- Ovarian Cancer
- Primary Peritoneal Cavity Cancer
Interventions
- DRUG
-
tamoxifen citrate
- OTHER
-
diagnostic laboratory biomarker analysis
Sponsors & Collaborators
-
Mount Vernon Cancer Centre at Mount Vernon Hospital
lead OTHER
Principal Investigators
-
Gordon J.S. Rustin, MD · Mount Vernon Cancer Centre at Mount Vernon Hospital
Study Design
- Purpose
- DIAGNOSTIC
- Masking
- NONE
Eligibility
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-03-31
- Primary Completion
- 2008-12-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission
NCT00522301 ·Status: TERMINATED ·Phase: PHASE2
-
Taurolidine in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
NCT00021034 ·Status: COMPLETED ·Phase: PHASE1
-
Capecitabine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT00004012 ·Status: COMPLETED ·Phase: PHASE2
-
Talazoparib in Determining Genetic Effects on Disease Response in Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT02316834 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Persistent or Recurrent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
NCT01468909 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy vs Hormonal Treatment in Platinum-resistant Ovarian Cancer Resistant or Refractory to Platinum and Taxane
NCT02728622 ·Status: COMPLETED ·Phase: PHASE3
-
CA-125 in Screening Patients at High Risk for Ovarian Cancer
NCT00080639 ·Status: WITHDRAWN
-
Phase 1/2a Evaluation of AL3818 in Subjects With Recurrent or Metastatic Endometrial, Ovarian or Cervical Cancer (AL3818-US-001)
NCT02558348 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Retrospective Case Study to Validate Existing Chemoresponse Marker Test in Ovarian, Peritoneal or Fallopian Cancer Cases
NCT01048814 ·Status: COMPLETED
-
Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer
NCT01372787 ·Status: UNKNOWN
-
Toremifene in Treating Patients With Ovarian Cancer
NCT00003865 ·Status: WITHDRAWN ·Phase: PHASE2
-
mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian
NCT02208375 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer
NCT02101788 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Intravital Microscopy in Evaluating Patients With Primary Peritoneal, Fallopian Tube, or Stage IA-IV Ovarian Cancer
NCT03297489 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
CT-2103 in Treating Patients With Recurrent Ovarian Epithelial or Fallopian Tube Cancer or Primary Peritoneal Cancer
NCT00017017 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy Consisting of Gemcitabine And Topotecan in Treating Patients With Refractory or Recurrent Ovarian or Fallopian Tube Cancer
NCT00003382 ·Status: TERMINATED ·Phase: PHASE1
-
Newly Diagnosed Stage III/IV Ovarian Cancer, Neoadjuvant Carbo/Taxol/Pembro, Maintenance Olaparib/Pembro
NCT05952453 ·Status: RECRUITING ·Phase: PHASE2
-
Docetaxel and Capecitabine in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cavity Cancer
NCT00354601 ·Status: TERMINATED ·Phase: PHASE2
-
Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
NCT03586661 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase II Study of ZD1839 and Tamoxifen in Patients With Epithelial Ovarian Carcinoma, Cancer of the Fallopian Tube or the Peritoneum Refractory to Platinum- and Taxane-based Therapy
NCT00189358 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Autologous Peripheral Stem Cell Transplant in Treating Patients With Stage III, Stage IV, or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
NCT00550784 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy to the Abdomen Plus Docetaxel in Treating Patients With Recurrent or Persistent Advanced Ovarian, Peritoneal, or Fallopian Tube Cancer
NCT00066456 ·Status: COMPLETED ·Phase: PHASE1
-
Panitumumab and Gemcitabine in Relapsed Ovarian Cancer
NCT01296035 ·Status: TERMINATED ·Phase: PHASE2
-
Predictors of Relapse of Ovarian, Peritoneal, and Fallopian Tube Cancers
NCT00086567 ·Status: COMPLETED
-
Clinical Trial to Screen Participants Who Are at High Genetic Risk for Ovarian Cancer
NCT00039559 ·Status: UNKNOWN ·Phase: NA