Influence of Treatment With Olanzapine or Ziprasidone on Transcapillary Glucose Transport in Human Skeletal Muscle
NCT00297960 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL
Last updated 2006-10-18
Summary
Healthy volunteers will undergo euglycaemic hyperinsulinaemic clamp and microdialysis before and after administration of 10mg olanzapine or 80mg ziprasidone during 10 days.
Conditions
- Healthy Male Volunteers
Interventions
- DRUG
-
ziprasidone or olanzapine
- PROCEDURE
-
hyperinsulinaemic euglycaemic clamp
- PROCEDURE
-
microdialysis (skeletal muscle)
Sponsors & Collaborators
-
Medical University of Vienna
lead OTHER
Principal Investigators
-
Siegfried Kasper, Prof. MD · Medical University Vienna, Department of General Psychiatry
Study Design
- Allocation
- RANDOMIZED
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-04-30
Countries
- Austria
Study Locations
More Related Trials
-
Acute Impact of Intramuscular (IM) Aripiprazole and Olanzapine on Insulin Resistance in High Risk Prediabetics
NCT01411930 ·Status: COMPLETED ·Phase: PHASE4
-
Glucose and Lipid Metabolism on Antipsychotic Medication
NCT00515723 ·Status: COMPLETED ·Phase: NA
-
Effect of Ziprasidone on Glucose & Plasma Lipids in Diabetes (II) and Schizophrenia or Schizoaffective Disorder
NCT00395031 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Dopamine and Insulin in Psychosis
NCT07252752 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effects of Antipsychotics on Brain Insulin Action in Females
NCT06251635 ·Status: RECRUITING ·Phase: NA
-
Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Antipsychotic Drugs in Healthy Humans
NCT00625170 ·Status: COMPLETED ·Phase: NA
-
Does GLP-1RA Prevent Deterioration of Metabolic State in Prediabetic and Diabetic Patients Treated With Antipsychotic Medication?
NCT04892199 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Effect of Short Term Atypical Antipsychotic Administration Compared to Placebo on Hepatic Insulin Extraction
NCT02447835 ·Status: COMPLETED ·Phase: PHASE1
-
One-Year Trial Of Oral Ziprasidone In Patients With Metabolic Syndrome
NCT00748566 ·Status: TERMINATED ·Phase: PHASE4
-
Examining the Effects of Antipsychotic Medications on Insulin Sensitivity
NCT00895921 ·Status: COMPLETED ·Phase: PHASE4
-
β-Cell Function in Schizophrenic Subjects on Atypical Antipsychotic drugS
NCT00528359 ·Status: COMPLETED
-
An Insulin Sensitivity Study in Healthy Subjects
NCT02922426 ·Status: COMPLETED ·Phase: PHASE1
-
Determining Metabolic Effects of Valproate and Antipsychotic Therapy
NCT00167934 ·Status: COMPLETED ·Phase: NA
-
Metabolic Effects of Antipsychotics in Children
NCT00205699 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Atypical Antipsychotic and Valproate Combination Therapy on Glucose and Lipid Metabolism in Schizophrenia
NCT00552500 ·Status: COMPLETED ·Phase: NA
-
Metabolic Outcomes in Patients With Prolactinomas Under Dopamine Agonist Treatment
NCT07045935 ·Status: RECRUITING ·Phase: PHASE4
-
Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Haloperidol in Healthy Humans
NCT00625014 ·Status: COMPLETED ·Phase: NA
-
Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia
NCT05748990 ·Status: RECRUITING ·Phase: NA
-
Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Antipsychotic-treated Patients?
NCT01845259 ·Status: UNKNOWN ·Phase: PHASE2
-
Antipsychotics and Risk of Hyperglycemic Emergencies
NCT02582736 ·Status: COMPLETED
-
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
NCT00682448 ·Status: COMPLETED ·Phase: PHASE4
-
Cross-Sectional Iloperidone IVGTT
NCT01686815 ·Status: COMPLETED
-
Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for Schizophrenia
NCT00794963 ·Status: TERMINATED ·Phase: NA
-
AP Metabolism Transcriptomics
NCT06814314 ·Status: RECRUITING
-
Treatment of Antipsychotic-associated Obesity With a GLP-1 Analogue
NCT01794429 ·Status: COMPLETED ·Phase: PHASE3