Forodesine Hydrochloride (BCX-1777) for B-Cell Acute Lymphoblastic Leukemia
NCT00289562 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2012-01-20
Summary
A Phase I/II, Multi-Center, Open-Label, Repeat-Dose Study of Forodesine Hydrochloride Infusion in Patients with B-cell Acute Lymphoblastic Leukemia with an Option of Extended Use of Forodesine Hydrochloride
Conditions
Interventions
- DRUG
-
forodesine hydrochloride (BCX-1777)
Sponsors & Collaborators
-
BioCryst Pharmaceuticals
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-09-30
- Primary Completion
- 2007-12-31
- Completion
- 2007-12-31
Countries
- United States
Study Locations
More Related Trials
-
A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias
NCT06994676 ·Status: RECRUITING ·Phase: PHASE1
-
CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
NCT03896269 ·Status: RECRUITING ·Phase: PHASE1
-
First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers
NCT01120457 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Safety and Tolerability of Weekly Intravenous (IV) Doses of BMS-906024 in Subjects With Acute T-cell Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
NCT01363817 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias
NCT01149915 ·Status: COMPLETED ·Phase: PHASE1
-
Hydroxychloroquine in Untreated B-CLL Patients
NCT00771056 ·Status: TERMINATED ·Phase: PHASE2
-
Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid Leukemia
NCT01804101 ·Status: COMPLETED ·Phase: NA
-
Mitoxantrone Hydrochloride Liposome Combined With Chemotherapy in Untreated de Novo Acute Myeloid Leukemia
NCT05941585 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase
NCT00449761 ·Status: TERMINATED ·Phase: PHASE2
-
FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies
NCT04891757 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Study of ADCT-402 in Patients With Relapsed or Refractory B-cell Lineage Acute Lymphoblastic Leukemia (B-ALL)
NCT02669264 ·Status: TERMINATED ·Phase: PHASE1
-
Dose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL
NCT04030195 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
8-Chloroadenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
NCT02509546 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study Evaluating Inotuzumab Ozogamicin In Acute Lymphocytic Leukemia
NCT01363297 ·Status: COMPLETED ·Phase: PHASE2
-
Immunotoxin Therapy and Cytarabine in Treating Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia
NCT01408160 ·Status: TERMINATED ·Phase: PHASE1
-
Decitabine and Bortezomib in Treating Patients With Acute Myeloid Leukemia
NCT00703300 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Combination With Low Intensity Chemotherapy in Older Patients With Newly Diagnosed B-cell Acute Lymphoblastic Leukemia
NCT07153796 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase I Study of MGCD0103 Given Three-Times Weekly In Patients With Leukemia Or Myelodysplastic Syndromes
NCT00324129 ·Status: COMPLETED ·Phase: PHASE1
-
7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes
NCT00301938 ·Status: COMPLETED ·Phase: PHASE1
-
8-Chloro-Adenosine in Chronic Lymphocytic Leukemia
NCT00714103 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Dose Escalation of BAY1143572 in Subjects With Acute Leukemia
NCT02345382 ·Status: COMPLETED ·Phase: PHASE1
-
Troxacitabine in Treating Patients With Chronic Myelogenous Leukemia
NCT00012259 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of HS-10382 in Patients With Chronic Myeloid Leukemia.
NCT05367700 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia
NCT06401603 ·Status: RECRUITING ·Phase: PHASE1
-
Trial of AVN-944 in Patients With Advanced Hematologic Malignancies
NCT00273936 ·Status: COMPLETED ·Phase: PHASE1