Antibiotic Resistant Helicobacter Pylori in Rajavithi Hospital
NCT00285688 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2020-10-19
Summary
Peptic ulcer disease is the most common gastrointestinal disease. Antibiotic resistant Helicobacter pylori is a major problem worldwide. The gold standard for Helicobacter pylori eradication is composed of Proton-pump inhibitor/Ranitidine bismuth citrate + Amoxycillin + Metronidazole /Clarithromycin. In Thailand, clarithromycin resistant strains increased and led to treatment failure. Data on file at Rajavithi Hospital showed that metronidazole resistant H. pylori was about 50% and Clarithromycin resistant strains accounted for 8%. This molecular genetic study will be performed in patients presenting with dyspepsia, who had an indication for gastroscopic examination, to explore the incidence of antibiotic resistant Helicobacter pylori in Rajavithi Hospital, Thailand.
Conditions
- Dyspepsia
Interventions
- PROCEDURE
-
gastroscopic examination
gastroscopic examination for tissue biopsy and real time PCR for gene study
Sponsors & Collaborators
-
Department of Medical Services Ministry of Public Health of Thailand
lead OTHER_GOV
Principal Investigators
-
Piyathida Harnsoomboon, MD · Department of Medical Services Ministry of Public Health of Thailand
Eligibility
- Min Age
- 15 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-06-30
- Primary Completion
- 2007-12-31
- Completion
- 2007-12-31
Countries
- Thailand
Study Locations
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