A Phase II, Open-Label Study Evaluating the Effect Of GW786034 In Subjects With Ovarian Cancer
NCT00281632 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 35
Last updated 2018-09-17
Summary
This study was designed to find out how effective and safe GW786034, is in the treatment of epithelial ovarian, fallopian tube, or primary peritoneal cancer that has not responded to standard treatment.
Conditions
- Peritoneal Cancer
- Ovarian Cancer
- Neoplasms, Ovarian
- Fallopian Tube Cancer
Interventions
- DRUG
-
GW786034
800 mg GW786034 administered orally on a daily basis.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials, MD · GlaxoSmithKline
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-03-31
- Primary Completion
- 2008-04-30
- Completion
- 2010-10-31
Countries
- United States
- Australia
- Singapore
Study Locations
More Related Trials
-
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
NCT06824467 ·Status: RECRUITING ·Phase: PHASE3
-
A Study to Evaluate rhuMab 2C4 and Gemcitabine in Subjects With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
NCT00096993 ·Status: COMPLETED ·Phase: PHASE2
-
CP-547,632 in Treating Patients With Recurrent or Persistent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
NCT00096239 ·Status: COMPLETED ·Phase: PHASE2
-
A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Dependent Kinases 4 and 6 in Patients With Recurrent Ovarian Cancer Demonstrating Rb-proficiency and Low p16 Expression
NCT01536743 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Pembrolizumab With or Without CC-486 in Patients With Platinum-resistant Ovarian Cancer
NCT02900560 ·Status: TERMINATED ·Phase: PHASE2
-
Oregovomab and PLD in PARP Inhibitor Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment
NCT05407584 ·Status: UNKNOWN ·Phase: PHASE2
-
Carboxyamidotriazole in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
NCT00019461 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
NCT00753480 ·Status: SUSPENDED ·Phase: PHASE1
-
SGI-110 in Combination With Carboplatin in Ovarian Cancer
NCT01696032 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of 2-h Infusion of ON 01910.Na in Ovarian Cancer Patients
NCT00856791 ·Status: COMPLETED ·Phase: PHASE2
-
The Activity of TroVax® Versus Placebo in Relapsed Asymptomatic Ovarian Cancer
NCT01556841 ·Status: COMPLETED ·Phase: PHASE2
-
Gefitinib in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer or Primary Peritoneal Cancer
NCT00023699 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of TRC105 in the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma
NCT01381861 ·Status: COMPLETED ·Phase: PHASE2
-
Pilot Study of Taxol, Carboplatin, and Bevacizumab in Advanced Stage Ovarian Carcinoma Patients
NCT00127920 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II CT-2103/Carboplatin in Ovarian Cancer
NCT00069901 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of ZL-2306 (Niraparib) as Maintenance Treatment Following First-line Chemotherapy in Patients With Advanced Ovarian Cancer
NCT03709316 ·Status: UNKNOWN ·Phase: PHASE3
-
An Open Label Study To Investigate the Pharmacokinetics and Pharmacodynamics of Repeat Escalating Doses of the Oral AKT Inhibitor GSK2141795 by 18F FDG PET Analysis in Subjects With Ovarian Cancer
NCT01266954 ·Status: COMPLETED ·Phase: PHASE1
-
Capecitabine in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal Cavity Cancer
NCT00006812 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II)
NCT01482715 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Trial on Trabectedin (ET-743) vs Clinician's Choice Chemotherapy in Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancers of BRCA Mutated or BRCAness Phenotype Patients
NCT02903004 ·Status: COMPLETED ·Phase: PHASE3
-
Ispinesib In Subjects With Platinum-Taxane-Refractory Or Resistant Relapsed Ovarian Cancer
NCT00097409 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in at Least the Second Remission
NCT00522301 ·Status: TERMINATED ·Phase: PHASE2
-
ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment
NCT00005645 ·Status: WITHDRAWN ·Phase: PHASE2
-
Correlation of the Chemoresponse Assay With PFS in Patients With Recurrent Epithelial Ovarian, Peritoneal, or Fallopian Tube Cancer
NCT00288275 ·Status: TERMINATED
-
Capecitabine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT00004012 ·Status: COMPLETED ·Phase: PHASE2