Telmisartan (Micardis) and Amlodipine (Norvasc) - Factorial Design Study for the Treatment of Hypertension

Summary

To demonstrate that Micardis and Norvasc when used together are more effective at lowering blood pre ssure.

Conditions

• Hypertension

Interventions

DRUG

Amlodipine 5 mg

Amlodipine 5 mg once daily for two weeks

DRUG

Placebo

Placebo to Telmisartan and Amlodipine once daily for eight weeks

DRUG

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

DRUG

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

DRUG

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

DRUG

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

DRUG

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

DRUG

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

DRUG

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

DRUG

Amlodipine 5 mg

Amlodipine 5 mg once daily for two weeks

DRUG

Amlodipine 5 mg

amlodipine 5g once daily for eight weeks

DRUG

Telmisartan 20 mg

Telmisartan 20 mg once daily for eight weeks

DRUG

Amlodipine 5 mg

Amlodipine 5 mg once daily for eight weeks

DRUG

Amlodipine 5 mg

amlodipine 5mg once daily for eight weeks

DRUG

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

DRUG

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

DRUG

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

DRUG

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

DRUG

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

DRUG

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

DRUG

Amlodipine 5 mg

Amlodipine 5 mg once daily for two weeks

DRUG

Amlodipine 2.5 mg

Amlodipine 2.5 mg once daily for eight weeks

DRUG

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

DRUG

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

DRUG

Amlodipine 5 mg

amlodipine 5g once daily for two weeks

DRUG

Amlodipine 5 mg

Amlodipine 5 mg once daily for eight weeks

DRUG

Telmisartan 40 mg

Telmisartan 40 mg once daily for eight weeks

DRUG

Telmisartan 80 mg

Telmisartan 80 mg once daily for eight weeks

DRUG

Amlodipine 10 mg

Amlodipine 10 mg once daily for six weeks

Sponsors & Collaborators

• Boehringer Ingelheim

  lead INDUSTRY

Principal Investigators

• Boehringer Ingelheim · Boehringer Ingelheim

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2006-04-30

Primary Completion

2007-03-31

Countries

• United States
• Argentina
• Brazil
• Mexico
• South Africa

Study Locations