TEDDY - The Environmental Determinants of Diabetes in the Young

Summary

The long-term goal of the TEDDY study is the identification of infectious agents, dietary factors, or other environmental agents, including psychosocial factors which trigger T1DM in genetically susceptible individuals or which protect against the disease. Identification of such factors will lead to a better understanding of disease pathogenesis and result in new strategies to prevent, delay or reverse T1DM.

Conditions

• Type 1 Diabetes Mellitus

Sponsors & Collaborators

• National Institute of Allergy and Infectious Diseases (NIAID)

  collaborator NIH

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  collaborator NIH

• National Institute of Environmental Health Sciences (NIEHS)

  collaborator NIH

• Juvenile Diabetes Research Foundation

  collaborator OTHER

• Centers for Disease Control and Prevention

  collaborator FED

• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

  lead NIH

Principal Investigators

• Jeffrey P. Krischer, PhD · University of South Florida

• Marian J. Rewers, MD, PhD · University of Colorado Health Science Center

• William A. Hagopian, MD, PhD · Pacific Northwest Research Institute

• Ake Lernmark, MD, PhD · Lund University

• Jorma Toppari, MD, PhD · Wellbeing Services County of Southwest Finland

• Richard McIndoe, PhD · Augusta University Research Institute, Inc.

• Anette G. Ziegler, MD · Diabetes Research Institute

• Beena Akolkar, PhD · National Institutes of Diabetes and Digestive Kidney Diseases

Eligibility

Min Age

0 Months

Max Age

4 Months

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2004-09-01

Primary Completion

2025-06-30

Completion

2025-06-30

Countries

• United States
• Finland
• Germany
• Sweden

Study Locations