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Outcomes Following Pulmonary Valve Replacement in Adults

NCT00276237 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2013-11-26

No results posted yet for this study

Summary

One of the most common residual lesions in adult survivors of pediatric cardiac surgery is pulmonary valve disease, particularly regurgitation.

Multiple studies have demonstrated that placement of a pulmonary valve in such patients, results in improved ventricular function and resolution of symptoms. However, the optimal prosthetic valve for use in the pulmonary position has not been defined. There are essentially three alternatives available: the stented bioprosthetic valve, stentless bioprosthetic "tube" grafts used to replace the entire right ventricular outflow tract and mechanical valves.

All three of these valve options have been used in adults with congenital heart disease at Emory Healthcare and at Children's Healthcare of Atlanta at Egleston.

The goal of this study is to evaluate and compare the indications and short and mid-term outcomes for these alternative therapies.

Conditions

  • Heart Disease, Congenital
  • Pulmonary Valve Replacement

Sponsors & Collaborators

  • Emory University

    lead OTHER

Principal Investigators

  • Paul M Kirshbom, MD · Emory University Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-07-31
Completion
2005-11-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00276237 on ClinicalTrials.gov