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Effects of Atorvastatin Versus Probucol on Small Dense LDL

NCT00276133 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2007-05-09

No results posted yet for this study

Summary

Small dense low-density lipoprotein (LDL) plays an important role in causing glomerular injury through conversion to an oxidatively modified form of LDL. However, few studies evaluated the effects of antilipidemic agents on the LDL particle size and renoprotective actions in hyperlipidemic patients with non-diabetic nephropathy.

Conditions

  • Chronic Nephropathy

Interventions

DRUG

Effects of atorvastatin versus probucol on small dense LDL

Sponsors & Collaborators

  • Yokohama City University Medical Center

    lead OTHER

Principal Investigators

  • Gen Yasuda, MD · Yokohama City University Center Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-01-31
Completion
2007-05-31

Countries

  • Japan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00276133 on ClinicalTrials.gov