Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole
NCT00268554 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2008-03-28
Summary
The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion. Furthermore we hypothesize that dipyridamole augments postocclusive reactive hyperaemia by increasing adenosine receptor stimulation.
Conditions
- Hyperemia
- Hypoxia
Interventions
- DRUG
-
dipyridamole
- DRUG
-
caffeine
Sponsors & Collaborators
-
Radboud University Medical Center
lead OTHER
Principal Investigators
-
Gerard Rongen, MD,PhD · Radboud University Medical Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-12-31
- Completion
- 2006-07-31
Countries
- Netherlands
Study Locations
More Related Trials
-
Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)
NCT00826280 ·Status: COMPLETED ·Phase: PHASE3
-
Adenosine Receptors Influence Ischemia-Reperfusion Injury
NCT00184847 ·Status: SUSPENDED ·Phase: NA
-
The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals
NCT00311974 ·Status: COMPLETED ·Phase: PHASE4
-
Vitamin C in Post-cardiac Arrest
NCT03509662 ·Status: COMPLETED ·Phase: PHASE2
-
Impact of Chronic and Acute Caffeine Intake on the Hematopoietic System
NCT07193264 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effects of Red Bull® on the Effects of Training and Haemodynamic Parameters
NCT04963556 ·Status: COMPLETED ·Phase: NA
-
Effects of Vasopressors on Immune Response
NCT02675868 ·Status: COMPLETED ·Phase: PHASE4
-
Food-effect Study on Uracil and Dihydrouracil Levels as a Diagnostic Marker of Dihydropyrimidine Dehydrogenase Activity
NCT02718664 ·Status: COMPLETED ·Phase: NA
-
Treatment of Reperfusion Event by Vitamin C Infusion
NCT01090895 ·Status: UNKNOWN ·Phase: PHASE4
-
The Effect of Phenylephrine and Ephedrine on Microvascular Blood Flow
NCT02252627 ·Status: UNKNOWN
-
Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation
NCT01311414 ·Status: WITHDRAWN ·Phase: NA
-
Does Caffeine Reduce Rosuvastatin-Induced Protection Against Ischemia-Reperfusion Injury?
NCT00457652 ·Status: COMPLETED ·Phase: PHASE4
-
Caffeine and Cerebrovascular Reactivity
NCT04730193 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Acute Caffeine Effects on Cardiac Autonomic and Cardiorespiratory Parameters Responses After Aerobic Exercise
NCT02917889 ·Status: UNKNOWN ·Phase: NA
-
Using DNA-Typing and Erythrocyte Microparticle Analysis to Detect Blood Doping
NCT03548766 ·Status: UNKNOWN ·Phase: PHASE3
-
CYP1A2 and ADORA2A Genotypes and Endurance Performance.
NCT06547307 ·Status: RECRUITING ·Phase: NA
-
Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) to Parameters of the Cardiovascular System in Humans
NCT01421979 ·Status: COMPLETED ·Phase: NA
-
Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary Aldosteronism
NCT02127840 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Caffeine on Myocardial Oxygenation
NCT04585854 ·Status: COMPLETED ·Phase: NA
-
Storage Lesion in Banked Blood Due to Disruption of Nitric Oxide (NO) Homeostasis
NCT01137656 ·Status: COMPLETED ·Phase: PHASE1
-
Cardiovascular Effects of Adderall in Healthy Adults.
NCT02979327 ·Status: COMPLETED ·Phase: PHASE4
-
Trial of Caffeine to Alleviate Dyspnea Related to Ticagrelor
NCT02311088 ·Status: TERMINATED ·Phase: PHASE2
-
Influence of Bedrest and Hypocaloric Nutrition on Endothelium-Dependent Vasoreactivity
NCT00175968 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV
NCT02323399 ·Status: RECRUITING ·Phase: PHASE4
-
The Influence of Methotrexate on the Metabolism and Vascular Effects of Adenosine in Humans
NCT00184886 ·Status: COMPLETED ·Phase: NA