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Evaluation of Pain Intensity During Bone Marrow Biopsy Performed With Inhalation of Pre-Mixed 50 Per Cent Nitrous Oxide and Oxygen Mixture.

NCT00219713 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 280

Last updated 2005-09-22

No results posted yet for this study

Summary

Bone marrow biopsy is a painful medical procedure often performed with local anesthetic.

Therefore a double-blind, randomized, controlled trial was carried out in 330 adult patients who where referred for bone marrow biopsy and aspiration. 164 were assigned to inhale an equimolar mixture of nitrous oxide and oxygen and 166 to inhale a placebo. Pain measurement used visual-analogue pain scales, which involve rating the intensity of pain on a horizontal ruler

Conditions

Interventions

DRUG

nitrous oxide and oxygen

Sponsors & Collaborators

  • Ministry of Health, France

    collaborator OTHER_GOV

  • Air Liquide Santé International

    collaborator INDUSTRY

  • Poitiers University Hospital

    lead OTHER

Principal Investigators

  • François GUILHOT, MD · Department of Oncology hematology and Cell therapy, University Hospital , 86021 Poitiers - FRANCE

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2000-03-31
Completion
2004-12-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00219713 on ClinicalTrials.gov