Phase II Trial of Gleevec and Taxotere as a Combined Regimen for Advanced Gastric Adenocarcinoma
NCT00209079 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2007-12-31
Summary
The purpose of this trial is to test the combination of Gleevec® (also known as imatinib mesylate) and Taxotere (also known as docetaxel) in patients with incurable stomach cancer. This study is being performed to see if the combination of Gleevec and Taxotere is an effective treatment for incurable stomach cancer with minimal side effects.
Conditions
- Gastric Adenocarcinoma
Interventions
- DRUG
-
Gleevec, Taxotere
Gleevec taken 4 times daily, 100 mg per tablet. Taxotere intravenously once a week for two weeks.
Sponsors & Collaborators
- collaborator INDUSTRY
-
Emory University
lead OTHER
Principal Investigators
-
John Kauh, MD · Emory University Winship Cancer Institute
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-09-30
- Primary Completion
- 2007-04-30
- Completion
- 2007-04-30
Countries
- United States
Study Locations
More Related Trials
-
Imatinib Mesylate and Gemcitabine in Treating Patients With Locally Advanced, Metastatic, or Recurrent Pancreatic Cancer
NCT00281996 ·Status: TERMINATED ·Phase: PHASE1
-
Study of Gleevec and Weekly Paclitaxel in Patients Aged 70 or Older With Advanced Non-small Cell Lung Cancer
NCT01011075 ·Status: COMPLETED ·Phase: PHASE2
-
Gleevec/Taxol for Patients With Uterine Papillary Serous Carcinoma
NCT00506779 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Imatinib Mesylate in Treating Patients With Recurrent Ewing's Family of Tumors or Desmoplastic Small Round-Cell Tumor
NCT00062205 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Stage IV Colorectal Cancer
NCT00041340 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Imatinib (Gleevec®) in Selected Patients With Metastatic Melanoma
NCT00881049 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I Trial of Fixed Dose STI571 (Imatinib Mesylate) With Escalating Doses of Docetaxel in Patients With Metastatic Androgen-Independent Prostate Cancer
NCT00038194 ·Status: COMPLETED ·Phase: PHASE1
-
Imatinib Mesylate in Treating Patients With Metastatic Melanoma
NCT00027586 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate After Irinotecan and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00248482 ·Status: COMPLETED ·Phase: PHASE2
-
Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST)
NCT00290485 ·Status: UNKNOWN ·Phase: PHASE2
-
Gemcitabine With or Without Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Kidney Cancer
NCT00323791 ·Status: TERMINATED ·Phase: PHASE2
-
Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor
NCT00028002 ·Status: COMPLETED ·Phase: PHASE2
-
BGJ398 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
NCT02257541 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
NCT01991379 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Gleevec Maintenance Therapy After Induction Irinotecan and Cisplatin in Patients With C-Kit Positive Extensive SCLC
NCT00156286 ·Status: COMPLETED ·Phase: PHASE2
-
Trial Evaluating Gleevec in Patients With Anaplastic Thyroid Carcinoma
NCT00115739 ·Status: TERMINATED ·Phase: PHASE2
-
Ph II Study of Perifosine Plus Gleevec for Patients With GIST
NCT00455559 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate and Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00045604 ·Status: COMPLETED ·Phase: PHASE1
-
TALL-104 and Gleevec in Chronic Myelogenous Leukemia Patients
NCT00415909 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine and Imatinib Mesylate in Treating Patients With Recurrent or Metastatic Non-Small Cell Lung Cancer
NCT00323362 ·Status: TERMINATED ·Phase: PHASE2
-
Treatment-free Remission After Achieving Sustained MR4.5 on Nilotinib (ENESTop)
NCT01698905 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Combination With Docetaxel for Advanced, Platinum-Refractory Ovarian Cancer
NCT00216112 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer
NCT00042952 ·Status: TERMINATED ·Phase: PHASE2
-
Gleevec Combined With Camptosar Plus Paraplatin in Previously Untreated Extensive Stage Small Cell Lung Cancer
NCT00193349 ·Status: COMPLETED ·Phase: PHASE2
-
Trastuzumab and Imatinib Mesylate in Treating Patients With Recurrent or Metastatic HER2/Neu-Expressing Cancer
NCT00084513 ·Status: COMPLETED ·Phase: PHASE1