Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST)
NCT00290485 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2006-04-07
Summary
The aim of this study is to demonstrate that the use of Gleevec in initially non-resectable gastrointestinal stromal tumors can lead to allow complete resection in 20% of cases.
Conditions
Interventions
- DRUG
-
Imatinib mesylate
Sponsors & Collaborators
-
Hippocrate Research & Development
collaborator UNKNOWN -
Maisonneuve-Rosemont Hospital
lead OTHER
Principal Investigators
-
Pierre Dubé, MD · Maisonneuve-Rosemont Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-08-31
Countries
- Canada
Study Locations
More Related Trials
-
Imatinib Mesylate in Treating Patients With Primary Gastrointestinal Stromal Tumor That Has Been Completely Removed By Surgery
NCT00041197 ·Status: COMPLETED ·Phase: PHASE3
-
Imatinib Mesylate in Treating Patients With Gastrointestinal Stromal Tumor That Has Been Completely Removed During Surgery
NCT00025246 ·Status: COMPLETED ·Phase: PHASE2
-
Adjuvant Imatinib in High-risk Gastrointestinal Stromal Tumor (GIST) With C-kit Mutation
NCT00278876 ·Status: COMPLETED ·Phase: PHASE2
-
Post-Marketing Clinical Study of Postoperative Adjuvant Therapy With Imatinib Mesylate in Patients With Gastrointestinal Stromal Tumors (GIST)
NCT00171977 ·Status: COMPLETED ·Phase: PHASE4
-
MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
NCT01991379 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Ph II Study of Perifosine Plus Gleevec for Patients With GIST
NCT00455559 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Locally Advanced Gastrointestinal Stromal Tumor
NCT00112632 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor
NCT00028002 ·Status: COMPLETED ·Phase: PHASE2
-
Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST)
NCT02260505 ·Status: COMPLETED ·Phase: PHASE3
-
Three Versus Five Years of Adjuvant Imatinib as Treatment of Patients With Operable GIST
NCT02413736 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Study Comparing 12 Months Versus 36 Months of Imatinib in the Treatment of Gastrointestinal Stromal Tumor (GIST)
NCT00116935 ·Status: COMPLETED ·Phase: PHASE3
-
Phase ll Study of Imatinib Mesylate for the Neoadjuvant Treatment of Patients With Gastrointestinal Stromal Tumors (GIST)
NCT01483014 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Liver Metastasis From a Gastrointestinal Stromal Tumor
NCT00764595 ·Status: COMPLETED ·Phase: PHASE2
-
Imatinib Mesylate in Treating Patients With Stage IV Colorectal Cancer
NCT00041340 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Tasigna (Nilotinib) 400 mg Twice Daily Alone or With Gleevec (Imatinib Mesylate) 400 mg Daily for Patients With Advanced Gastrointestinal Stromal Tumor (GIST)
NCT01089595 ·Status: TERMINATED ·Phase: PHASE2
-
A Study To Assess The Safety And Efficacy Of SU11248 In Patients With Gastrointestinal Stromal Tumor(GIST)
NCT00075218 ·Status: COMPLETED ·Phase: PHASE3
-
Prospective Multicentric Randomized Study of Glivec® in Advanced GIST Expressing C-kit: Interruption After 5 Years vs Maintenance
NCT00367861 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST
NCT01294202 ·Status: COMPLETED ·Phase: PHASE2
-
Long-term Surival of GIST Patients ≥ 10 Years on Imatinib
NCT04097093 ·Status: WITHDRAWN
-
Imatinib TDM in GIST
NCT05493215 ·Status: RECRUITING ·Phase: PHASE2
-
Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal Tumors
NCT04933669 ·Status: RECRUITING ·Phase: PHASE2
-
A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments
NCT05152472 ·Status: RECRUITING ·Phase: PHASE2
-
Open-label Trial of GlivecWith Unresectable or Metastatic Malignant Gastrointestinal Stromal Tumors
NCT00293124 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Two Different Doses of STI571 in Treating Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumor
NCT00009906 ·Status: TERMINATED ·Phase: PHASE3
-
Study of Imatinib and Peginterferon α-2b in Gastrointestinal Stromal Tumor (GIST) Patients
NCT00585221 ·Status: TERMINATED ·Phase: PHASE2