MedTrace Logo

Oral Misoprostol Before Endometrial Biopsy

NCT00200226 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2007-09-21

No results posted yet for this study

Summary

An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus. Sometimes there may be discomfort with this procedure especially if the cervix is not dilated or opened. Previous research has suggested that taking a drug called misoprostol may help the cervix to start to dilate or open. This study will see if misoprostol will help open the cervix for an endometrial biopsy, to lessen the discomfort and make the biopsy easier to perform.

Conditions

  • Endometrial Biopsy

Interventions

DRUG

misoprostol

misoprostol 400mcg 12 hrs prior to procedure

DRUG

vitamin B6

Vitamin B6 50 mg orally 12 hrs prior to procedure

Sponsors & Collaborators

  • Memorial University of Newfoundland

    lead OTHER

Principal Investigators

  • Joan MG Crane, MD · Faculty, Discipline Obstetrics and Gynecology, Memorial University of Newfoundland

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
SINGLE_GROUP

Eligibility

Min Age
19 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2003-02-28
Completion
2007-09-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00200226 on ClinicalTrials.gov