Phase II Study of Alimta (Pemetrexed) Treatment of Advanced Thymoma and Thymic Carcinoma
NCT00198133 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 27
Last updated 2019-07-22
Summary
To study the efficacy of Alimta as a single agent in thymic cancers
Conditions
- Thymoma
- Thymic Carcinoma
Interventions
- DRUG
-
Premetrexed (Alimta)
Pemetrexed will be 500 mg/m2 IV every 3 weeks
Sponsors & Collaborators
-
Patrick Joseph Loehrer Sr.
lead OTHER
Principal Investigators
-
Patrick Loehrer, M.D. · Indiana University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-01-31
- Primary Completion
- 2006-12-31
- Completion
- 2012-05-31
Countries
- United States
Study Locations
More Related Trials
-
Octreotide With or Without Prednisone in Treating Patients With Metastatic or Recurrent Thymoma
NCT00003283 ·Status: COMPLETED ·Phase: PHASE2
-
Geldanamycin Analogue in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma
NCT00019708 ·Status: TERMINATED ·Phase: PHASE1
-
Preoperative Treatment of Patients With High Risk Thymoma
NCT00387868 ·Status: COMPLETED ·Phase: PHASE2
-
Campath-1H for Treating Adult T-Cell Leukemia/Lymphoma
NCT00061048 ·Status: COMPLETED ·Phase: PHASE2
-
IMRT Followed by Pembrolizumab in the Adjuvant Setting in Anaplastic Cancer of the Thyroid (IMPAACT): Phase II Trial Adjuvant Pembrolizumab After IMRT in ATC
NCT05059470 ·Status: TERMINATED ·Phase: PHASE2
-
Thalidomide in Mucosa Associated Lymphoid Tissue (MALT) Lymphoma Patients
NCT00373646 ·Status: COMPLETED ·Phase: PHASE2
-
Study Of Oral PHA-848125AC In Patients With Malignant Thymoma Previously Treated With Multiple Lines Of Chemotherapy
NCT01301391 ·Status: TERMINATED ·Phase: PHASE2
-
Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma
NCT04417660 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Alemtuzumab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV T-Cell Non-Hodgkin's Lymphoma
NCT00363090 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of Enasidenib in People With T-Cell Lymphoma
NCT06756308 ·Status: RECRUITING ·Phase: PHASE2
-
Pembrolizumab and Epacadostat in Patients With Thymic Carcinoma
NCT02364076 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Study of RT-PEPC in Relapsed Mantle Cell Lymphoma
NCT00151281 ·Status: COMPLETED ·Phase: PHASE2
-
Belinostat (PXD101) to Treat Tumors of the Thymus at an Advanced Stage
NCT00589290 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Study Of Oral PHA-848125AC In Patients With Thymic Carcinoma
NCT01011439 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Bortezomib and Panobinostat in Treating Patients With Relapsed/Refractory Peripheral T-cell Lymphoma or NK/T-cell Lymphoma
NCT00901147 ·Status: COMPLETED ·Phase: PHASE2
-
Atezolizumab With Chemotherapy in Treating Patients With Anaplastic or Poorly Differentiated Thyroid Cancer
NCT03181100 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, Malignancies
NCT01100944 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Pemigatinib in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphomas
NCT06300528 ·Status: RECRUITING ·Phase: PHASE2
-
Antineoplaston Therapy in Treating Patients With High-Grade Stage II - Stage IV Non-Hodgkin's Lymphoma
NCT00003501 ·Status: TERMINATED ·Phase: PHASE2
-
IPH4102/Lacutamab Alone or in Combination With Chemotherapy in Patients With Advanced T Cell Lymphoma
NCT03902184 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Rituximab in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma
NCT00007865 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic Malignancies
NCT01364727 ·Status: COMPLETED ·Phase: PHASE2
-
Alefacept in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma or Peripheral T-Cell Non-Hodgkin's Lymphoma
NCT00438802 ·Status: COMPLETED ·Phase: PHASE1
-
Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors
NCT05071209 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM)
NCT03134118 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2