MedTrace Logo

A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder

NCT00188942 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2013-02-08

No results posted yet for this study

Summary

This study employs functional magnetic resonance imaging to compare brain activation patterns during a depressive episode in patients diagnosed with bipolar disorder, major depressive disorder, and a group of healthy control subjects. Depressed patients will be treated with a combination of fluoxetine and olanzapine and undergo MRI scans before, during, and after pharmacotherapy.

Conditions

Interventions

DRUG

Fluoxetine+Olanzapine

DRUG

Olanzapine

PROCEDURE

Functional Magnetic Resonance Imaging

Sponsors & Collaborators

Principal Investigators

  • Sidney H. Kennedy, MD, FRCPC · University Health Network, Department of Psychiatry, University of Toronto

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-02-28
Primary Completion
2009-06-30
Completion
2009-06-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00188942 on ClinicalTrials.gov