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Radiation Dosimetry in Teeth

NCT00178347 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2009-05-19

No results posted yet for this study

Summary

Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).

It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.

Conditions

  • Radiation Tolerance

Interventions

RADIATION

Exposure to irradiation

Treatment for Cancer using Radiation -dose will be the standard of Care for the type of Cancer being treated

Sponsors & Collaborators

  • University of Rochester

    lead OTHER

Principal Investigators

  • Paul Okunieff, MD · University of Rochester, Dept. of Radiation Oncology

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00178347 on ClinicalTrials.gov