Pharmacokinetics of THCCOOH and Its Acyl-glucuronide After Intravenous Administration of THCCOOH
NCT00176085 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10
Last updated 2015-05-28
Summary
A study on the fate and elimination of 11-Nor-Delta9-carboxy-9-tetrahydrocannabinol was up to now not conducted, except of one single experiment in which (lacking) psychopharmacological activity was tested after intravenous infusion of 20 mg in a human individual. In this study, however, the authors did not trace the above questions due to analytical and methodological deficits.
Aim of the study is to determine the pharmacokinetics of THCCOOH and THCCOOH-Glu after intravenous ad-ministration of 5 mg THCCOOH in healthy individuals
Conditions
- THCCOOH
- Pharmacokinetics
- Metabolism
- Cannabis
Sponsors & Collaborators
-
Heidelberg University
lead OTHER
Principal Investigators
-
Gerd Mikus, MD BSc · Department of Internal Medicine VI
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2004-10-31
- Completion
- 2005-03-31
Countries
- Germany
Study Locations
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