Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions
NCT00171964 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 75
Last updated 2017-06-01
Summary
It is the aim of this multicentric clinical study to assess the efficacy and tolerability of zoledronic acid in combination with radiotherapy in patients with advanced osteolytic bone lesions in terms of the reduction of pain and analgesic consumption.
Conditions
Interventions
- DRUG
-
Zoledronic acid in combination with therapy
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmaceuticals
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-05-31
- Primary Completion
- 2008-12-31
- Completion
- 2008-12-31
Countries
- Germany
Study Locations
More Related Trials
-
S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases
NCT00874211 ·Status: COMPLETED
-
Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement
NCT00869206 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease
NCT00099203 ·Status: TERMINATED ·Phase: PHASE3
-
A Randomized Trial Evaluating Rapid Delivery of Dose Escalated Hypofractionated Radiotherapy for Patients Diagnosed With Bone Metastases for Effective Palliation of Symptoms
NCT02163226 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Zoledronic Acid Treatment on Bone-related Events in Breast Cancer Patients With Bone Metastases: a Prospective, Multicenter, Real-world Study
NCT05480189 ·Status: NOT_YET_RECRUITING
-
Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain
NCT03523351 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss
NCT00352846 ·Status: COMPLETED ·Phase: PHASE3
-
A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.
NCT00321464 ·Status: COMPLETED ·Phase: PHASE3
-
Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
NCT00742924 ·Status: COMPLETED ·Phase: PHASE1
-
Docetaxel and Prednisolone With or Without Zoledronic Acid and/or Strontium Chloride Sr 89 in Treating Patients With Prostate Cancer Metastatic to Bone That Has Not Responded to Hormone Therapy
NCT00554918 ·Status: COMPLETED ·Phase: PHASE2
-
Non Steroidal Anti-inflammatory Drugs in the Prevention of Bone Pain Flares After Palliative Radiotherapy
NCT06903585 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Chemotherapy and Radiotherapy for Osteolymphoma
NCT00141648 ·Status: COMPLETED ·Phase: NA
-
Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone
NCT00458796 ·Status: TERMINATED ·Phase: NA
-
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia or Acute Leukemia
NCT00004905 ·Status: COMPLETED ·Phase: PHASE2
-
M3541 in Combination With Radiotherapy in Solid Tumors
NCT03225105 ·Status: TERMINATED ·Phase: PHASE1
-
Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma
NCT03858205 ·Status: RECRUITING ·Phase: NA
-
Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
NCT02517918 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Zometa and Physical Activity on Bone Density in Women Receiving Chemotherapy for Breast Cancer
NCT00202059 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)
NCT01204203 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Aggressive Non-Hodgkin's Lymphoma
NCT00003815 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
NCT00004903 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma
NCT00002599 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy and Radiation Therapy Plus Bone Marrow Transplantation in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
NCT00002481 ·Status: UNKNOWN ·Phase: PHASE2
-
Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma
NCT06492954 ·Status: RECRUITING ·Phase: PHASE1
-
Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy
NCT01871766 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2