Multi-Center Prospective Randomized Trial Comparing Standard Esophagectomy Against Chemo-Radiotherapy for Treatment of Squamous Esophageal Cancer - Early Results From the Chinese University Research Group for Esophageal Cancer (CURE)
NCT00165061 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2005-09-14
Summary
A multicenter randomized comparison of primary esophagectomy against definitive chemoradiotherapy for the treatment of squamous esophageal cancer.
Conditions
- Esophageal Cancer
Interventions
- PROCEDURE
-
Esophagectomy
- PROCEDURE
-
Chemoradiation
Sponsors & Collaborators
-
Chinese University of Hong Kong
lead OTHER
Principal Investigators
-
Philip WY Chiu, MBChB, FRCSEd · Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong
-
Angus CW Chan, MD · Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-07-31
Countries
- China
Study Locations
More Related Trials
-
Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer
NCT01216527 ·Status: UNKNOWN ·Phase: PHASE3
-
Comparison Between NCRT and NCT Followed by MIE for Treatment of Locally Advanced Resectable ESCC
NCT03001596 ·Status: COMPLETED ·Phase: NA
-
A Study to Compare Efficacy and Safety of DRT VS CRT Plus Surgery in Patients Who Achieved CCR for Esophageal Cancer
NCT03708042 ·Status: UNKNOWN ·Phase: PHASE3
-
Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma
NCT03600831 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Study of Simultaneous Modulated Accelerated Radiation Therapy Concurrent With Chemotherapy to Treat Esophageal Cancer
NCT01670409 ·Status: COMPLETED ·Phase: PHASE2
-
Minimally Residual of Esophageal Cancer 001
NCT05952661 ·Status: RECRUITING
-
A Real-world Study Evaluating the Usage of Camrelizumab in Chinese Patients With Advanced Esophageal Cancer
NCT04616040 ·Status: NOT_YET_RECRUITING
-
Postoperative Radiotherapy in Thoracic Esophageal Squamous Cell Carcinoma With Neoadjuvant Chemoradiotherapy
NCT03734952 ·Status: RECRUITING ·Phase: NA
-
Role of Esophagectomy in Complete Responders to CCRT
NCT01740375 ·Status: TERMINATED ·Phase: PHASE3
-
Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy
NCT06602843 ·Status: RECRUITING ·Phase: NA
-
S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer
NCT02813967 ·Status: COMPLETED ·Phase: PHASE3
-
Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma
NCT04275986 ·Status: UNKNOWN ·Phase: PHASE2
-
Postoperative Radiotherapy Followed by Immunotherapy for Locally Advanced Esophageal Carcinoma
NCT05937438 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Simultaneous Modulated Accelerated Boost Versus Standard Dose Radiotherapy in Esophageal Cancer
NCT02556762 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Chemoradiotherapy Plus Immunotherapy Followed by Surgery for Esophageal Cancer
NCT04776590 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Different Radiation Dose With Concurrent Chemotherapy for Thoracic Esophageal Carcinoma
NCT02850991 ·Status: COMPLETED ·Phase: NA
-
Definitive (Chemo)Radiotherapy for Patients With Esophageal Cancer - 3JECROG R-01
NCT03298204 ·Status: COMPLETED
-
Esophageal Arterial Infusion Chemotherapy Versus Systemic Intravenous Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Prospective, Multicentre, Randomised Controlled Clinical Study
NCT05381636 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase II Trial to Compare Efficacy and Safety of CRT VS Neo-CRT in Patients Who Achieved CCR for Esophageal Cancer
NCT02959385 ·Status: UNKNOWN ·Phase: PHASE2
-
Phase II Study of Neo-adjuvant Chemoradiotherapy for Squamous Cell Esophageal Cancer
NCT02938195 ·Status: UNKNOWN ·Phase: PHASE2
-
Different Radiation Dose of Neoadjuvant Chemoradiation for Resectable Thoracic Esophageal Squamous Carcinoma
NCT03381651 ·Status: COMPLETED ·Phase: NA
-
Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center, Prospective, Open, One Arm Exploratory Clinical Study
NCT05028231 ·Status: UNKNOWN
-
Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy Concurrent With Chemotherapy for Esophageal Squamous Cell Carcinoma
NCT02916511 ·Status: COMPLETED ·Phase: PHASE2
-
Synchronous or Sequential Radiotherapy for Advanced Esophageal Squamous Cell Carcinoma With Oligometastases.
NCT06143722 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer
NCT06421376 ·Status: RECRUITING ·Phase: PHASE2