Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.
NCT00151788 · Status: TERMINATED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 796
Last updated 2012-01-18
Summary
The effects of pactimibe versus placebo on the progression of atherosclerosis in the carotid arteries will be assessed using standard ultrasound techniques.
Conditions
- Atherosclerosis
- Heterozygous Familial Hypercholesterolemia
Interventions
- DRUG
-
Pactimibe sulfate
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-02-29
- Primary Completion
- 2006-03-31
- Completion
- 2006-03-31
Countries
- United States
- Canada
- Israel
- Netherlands
- Norway
- South Africa
- Spain
- Sweden
- United Kingdom
Study Locations
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