CHIZAP: Community- and Health Facility-Based Intervention With Zinc as Adjuvant Therapy for Childhood Pneumonia

Summary

The aim of the study described is to measure the degree with which zinc given as adjunct therapy to standard antibiotic treatment during childhood pneumonia reduces the risk of treatment failure and the duration of the illness.

Conditions

• Pneumonia

Interventions

DRUG

Zinc

Dissolvable zinc tablet 10 mg elemental zinc per day for infants 20 mg elemental zinc per day for children 12 to 35 months

Sponsors & Collaborators

• Tribhuvan University, Nepal

  collaborator OTHER

• Statens Serum Institut

  collaborator OTHER

• All India Institute of Medical Sciences

  collaborator OTHER

• IRD, Epidemiologie et Prevention, Montpelier, France

  collaborator UNKNOWN

• Society for Applied Studies

  collaborator OTHER

• Centre For International Health

  lead OTHER

Principal Investigators

• Tor A Strand, MD PhD · Centre for International Health, University of Bergen, 5021 Bergen, Norway

• Halvor Sommerfelt, MD PhD · Centre for International Health, University of Bergen, 5021 Bergen, Norway

• Prakash S Shrestha, MD Professor · Child Health Research Project, Department of Child Health, Institute of Medicine, Maharajganj

• Ramesh K Adhikari, MD Dean · Child Health Research Project, Department of Child Health, Institute of Medicine, Maharajganj

• Palle Valentiner-Branth, MD PhD · Department of Epidemiology Research, Statens Serum Institut, 2300 Copenhagen S, Denmark

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

2 Months

Max Age

3 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2004-01-31

Primary Completion

2008-01-31

Completion

2008-01-31

Countries

• Nepal

Study Locations