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ADVANCE CRT - D: Antitachycardia Pacing (ATP) Delivery for Painless Implantable Cardioverter Defibrillator (ICD) Therapy

NCT00147290 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 526

Last updated 2025-07-02

Study results available
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Summary

To compare the efficacy of RV and BiV ATP for the termination of ventricular arrhythmias in patients who are candidates to a cardiac resynchronisation therapy (CRT) and have a Class I or IIA indication for ICD implantation.

The hypothesis of delivering ATP from different sites (RV or BIV) has never been evaluated in a prospective, controlled and randomized study.

Conditions

  • Tachycardia, Ventricular
  • Ventricular Fibrillation

Interventions

DEVICE

Implantable Cardiac Defibrillator

Implantable cardiac defibrillator with programmable Fast Ventricular tachycardia detection (FVT) window

Sponsors & Collaborators

  • Medtronic Cardiac Rhythm and Heart Failure

    lead INDUSTRY

Principal Investigators

  • Maurizio Gasparini, Dr. · Istituto Clinico Humanitas Mirasole SpA

  • Mario Bocchiardo, Dr. · Ospedale Civile di Asti

  • Antonio Curnis, Dr. · Spedali Civili di Brescia

  • Rafael Peinado, Dr. · La Paz Madrid

  • Philippe Mabo, Prof. · Rennes University Hospital

  • Thomas Lavergne, Dr. · E. H. Pompidou - Paris

  • Frederic Anselme, Dr. · University Hospital, Rouen

  • Joerg Schwab, Dr. · University Clinic - Bonn

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-02-29
Primary Completion
2007-04-30
Completion
2008-01-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00147290 on ClinicalTrials.gov