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Comparison of Facility and Home-based ART Delivery Systems in Uganda

NCT00144365 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1453

Last updated 2012-09-11

No results posted yet for this study

Summary

The study is a 3-year, randomized trial to compare ART delivery through two different models: a) ART delivered through health facilities by clinically qualified staff and b) home-based care in which lay workers, i.e. non-medically qualified people, play a major role in the ART delivery and clients are followed up at health facilities less frequently. The primary objective is to measure the effects of these strategies on HIV viral load. We will also examine the effects on treatment failure, disease progression, survival, adherence, family member HIV testing, sexual behavior, and cost-effectiveness.

Conditions

  • AIDS

Interventions

DRUG

Antiretroviral therapy

Sponsors & Collaborators

Principal Investigators

  • Heiner Grosskurth, MD, PhD · British Medical Research Council

  • Rebecca Bunnell, ScD, MEd · Centers for Disease Control and Prevention

  • Shabbar Jaffar, PhD · London School of Tropical Medicine and Hygeine

  • Alex Coutinho, MBChB, MSc · The AIDS Support Organization

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-02-28
Primary Completion
2008-12-31
Completion
2010-12-31

Countries

  • Uganda

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00144365 on ClinicalTrials.gov