Effects of Eplerenone on Left Ventricular Remodelling Following Heart Attack
NCT00132093 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2006-04-10
Summary
The purpose of this study is to ascertain whether treatment with the drug eplerenone, taken early after a heart attack, prevents or reduces some of the adverse changes that may otherwise naturally occur within the heart muscle, that lead ultimately to weakening of the heart muscle and premature death.
Conditions
Interventions
- DRUG
-
Eplerenone
Sponsors & Collaborators
-
NHS Greater Glasgow and Clyde
lead OTHER
Principal Investigators
-
Robin AP Weir, MBChB, BSc, MRCP · NHS Greater Glasgow and Clyde
-
Henry J Dargie, MBChB,FRCP · NHS Greater Glasgow and Clyde
-
John JV McMurray, FRCP,MD,FESC · University of Glasgow
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-04-30
Countries
- United Kingdom
Study Locations
More Related Trials
-
Endothelin-Receptor Blockade in Coronary Heart Disease
NCT00427232 ·Status: COMPLETED ·Phase: PHASE1
-
Exenatide for Myocardial Protection During Reperfusion Study
NCT01938235 ·Status: UNKNOWN ·Phase: PHASE2
-
The Effect of Ischaemic-Reperfusion in Man - A Bradykinin Dependent Pathway
NCT00965120 ·Status: COMPLETED ·Phase: NA
-
Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction
NCT01372930 ·Status: UNKNOWN ·Phase: PHASE4
-
IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack
NCT06139328 ·Status: TERMINATED ·Phase: PHASE2
-
Low Dose Interleukin-2 in Patients With Stable Ischaemic Heart Disease and Acute Coronary Syndromes
NCT03113773 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Clinical Study to Examine the Effects of Erythropoietin on Left Ventricular Function After Acute Myocardial Infarction
NCT00449488 ·Status: COMPLETED ·Phase: PHASE2
-
Heart Attack Blood Oxygen Therapy Trial
NCT06662890 ·Status: RECRUITING ·Phase: NA
-
COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial
NCT02404376 ·Status: COMPLETED ·Phase: PHASE3
-
Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients
NCT05604131 ·Status: RECRUITING ·Phase: PHASE2
-
Myocardial Protection With Adenosine During Primary Percutaneous Coronary Intervention in Pts With STEMI
NCT00781404 ·Status: COMPLETED ·Phase: PHASE3
-
Intracoronary Stenting and Antithrombotic Regimen: Lesion Platelet Adhesion as Selective Target of Endovenous Revacept
NCT03312855 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 2 Study to Evaluate the Efficacy, Safety and PK of Intravenous Single Injection LC28-0126 Immediately Before PCI in STEMI Patients
NCT02070471 ·Status: COMPLETED ·Phase: PHASE2
-
Nitrites in Acute Myocardial Infarction
NCT01388504 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of Permanent Right Internal Mammary Artery Occlusion on Extracardiac Coronary Collateral Supply
NCT03950947 ·Status: COMPLETED ·Phase: NA
-
Impact of Ischemic Post-conditioning
NCT04068116 ·Status: UNKNOWN ·Phase: NA
-
Concomitant Milrinone and Esmolol Treatment in Patients with Acute Myocardial Infarction
NCT02098629 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison of Standard Treatment Versus Standard Treatment Plus Extracorporeal Life Support (ECLS) in Myocardial Infarction Complicated With Cardiogenic Shock
NCT00314847 ·Status: TERMINATED ·Phase: PHASE4
-
Cardiovascular Magnetic Resonance for the Occluded Infarct-Related Artery Treatment
NCT00968383 ·Status: TERMINATED ·Phase: NA
-
Endothelin Receptor Blockade in Acute ST-elevation Myocardial Infarction
NCT00502528 ·Status: COMPLETED ·Phase: PHASE2
-
DLBS1033 for Acute NSTEMI Without Early Coronary Revascularization
NCT02146664 ·Status: WITHDRAWN ·Phase: PHASE2/PHASE3
-
Which Therapy for Acute Heart Attacks? (The WEST Study)
NCT00121446 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Clinical Outcomes of Angioplasty Postconditioning
NCT00419198 ·Status: COMPLETED ·Phase: NA
-
Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction
NCT04731155 ·Status: RECRUITING ·Phase: PHASE4
-
β Blocker Use and Mortality in Hospital Survivors of Acute Myocardial Infarction Without Heart Failure
NCT02786654 ·Status: COMPLETED