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Myocardial Protection With Adenosine During Primary Percutaneous Coronary Intervention in Pts With STEMI

NCT00781404 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 201

Last updated 2013-02-18

No results posted yet for this study

Summary

OBJECTIVE: to evaluate the safety and efficacy of a brief intracoronary infusion of ADO applied at the time of reperfusion to limit infarct size and LV remodelling in patients with ACSST submitted to primary ACTP.

DESIGN: Multicentric, prospective, randomised, parallel, placebo-controlled double-blind study.

PATIENTS: 200 patients older than 18 with ACSST and without prior myocardial infarction receiving primary PTCA within 6 hours after symptom onset.

Conditions

  • Acute Myocardial Infarction

Interventions

DRUG

Adenosine

Single dose of adenosine. Solution for infusion of 0.45 mg/mL. Enteral use.

Sponsors & Collaborators

  • Hospital General Universitario Gregorio Marañon

    collaborator OTHER

  • Hospital Clínico Universitario de Valladolid

    collaborator OTHER

  • Hospital Universitario Virgen Macarena

    collaborator OTHER

  • Instituto de Ciencias del Corazon

    collaborator OTHER

  • David Garcia-Dorado

    lead OTHER

Principal Investigators

  • David García-Dorado, MD, PhD · Valle Hebron Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-10-31
Primary Completion
2012-05-31
Completion
2012-07-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00781404 on ClinicalTrials.gov