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Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel

NCT00131885 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2023-11-13

Study results available
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Summary

This study will determine the effects of St. John's wort, a common herbal remedy, on metabolism of the female contraceptive hormone levonorgestrel.

Conditions

  • Contraception

Interventions

DIETARY_SUPPLEMENT

Placebo Control (Placebo Herb)

Placebo herb three times daily (ground cellulose) for 4-6 weeks

DIETARY_SUPPLEMENT

St. John's Wort

St. John's Wort (Hypericum perforatum) orally or 4-6 weeks

DRUG

Levonorgestrel

Levonorgestrel in a single oral dose

Sponsors & Collaborators

  • National Center for Complementary and Integrative Health (NCCIH)

    collaborator NIH

  • University of Utah

    lead OTHER

Principal Investigators

  • Patricia A. Murphy, DrPH · College of Nursing, University of Utah

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-08-31
Primary Completion
2008-05-31
Completion
2008-05-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00131885 on ClinicalTrials.gov