Left Ventricular Function After Acute Myocardial Infarction (AMI). Treatment With Angiotensin 2-Receptor Blockade (GLOBAL-Study)
NCT00125645 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2018-05-08
Summary
The purpose of this study is to compare changes in global left ventricular (LV) function after 3 months of treatment with irbesartan compared with usual care in patients with acute myocardial infarction, a wall motion score \>1.3 (EF\>0.40) and signs of diastolic dysfunction. The hypothesis is that an angiotensin 2-receptor inhibitor will improve global left ventricular function.
Conditions
Interventions
- DRUG
-
Irbesartan Oral Tablet
Sponsors & Collaborators
- collaborator INDUSTRY
-
University of Southern Denmark
lead OTHER
Principal Investigators
-
Kenneth Egstrup, Asst. Professor · Department of Medical Research, SHF Svendborg
Study Design
- Allocation
- NA
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-03-01
- Primary Completion
- 2011-09-01
- Completion
- 2011-09-01
Countries
- Denmark
Study Locations
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