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A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases

NCT00124761 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2010-09-06

No results posted yet for this study

Summary

This study examines surgery versus radiosurgery (highly focussed radiation) for the treatment of cancer which has spread to one spot in the brain (solitary brain "metastasis"). For these two treatment options, it will compare patients' survival times, quality of life, control rate of the brain metastases and side effects. It uses the most rigorous scientific method available called "randomisation" which minimises biases that exist with other types of studies. It will involve 30 - 40 patients.

Conditions

  • Neoplasm Metastasis
  • Brain Neoplasm

Interventions

PROCEDURE

Surgery + WBRT

Surgery - complete excision of Solitary Brain Metastasis with 30 Gy in 10 fractions over 2 2 1/2 weeks

RADIATION

Radiosurgery + WBRT

Radiosurgery - Marginal dose based on maximum tumour diameter

Sponsors & Collaborators

  • Royal Adelaide Hospital

    lead OTHER

Principal Investigators

  • Daniel Roos, MD, FRANZCR · Royal Adelaide Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-12-31
Primary Completion
2009-04-30
Completion
2009-05-31

Countries

  • Australia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00124761 on ClinicalTrials.gov