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Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPD

NCT00117182 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 140

Last updated 2016-04-20

No results posted yet for this study

Summary

The purpose of this study is to determine whether the Aridol (mannitol) challenge test can predict response to treatment with inhaled corticosteroids in COPD subjects. Subjects will undergo an Aridol test and then 3 months of treatment with inhaled corticosteroids. The effect on lung function and quality of life will then be measured and correlated with the Aridol test result.

Conditions

  • Lung Diseases, Obstructive

Interventions

DRUG

Dry powder mannitol

DRUG

Budesonide 400mcg administered via turbuhaler

DRUG

Ipratropium bromide 80mcg

DRUG

Salbutamol 400mcg

Sponsors & Collaborators

  • Syntara

    lead INDUSTRY

Principal Investigators

  • Alvin Ing, MBBS · Bankstown Hospital

  • Martin Coffey, MBBS · Rosebud Medical Centre

  • David Langton, MBBS · Peninsula Chest Clinic, Frankston

  • Chris Steinfort, MBBS · The Rooms of Dr Steinfort, Geelong

  • Trevor WIlliams, MBBS · The Alfred

  • Peter Frith, MBBS · Flinders Medical Centre

  • Michael Chia, MBBS · Respiratory Research Foundation, Toorak Gardens

  • Maureen McKeirnan, MBBS · Brisbane South Medical Centre

  • Fred de Looze, MBBS · Centre for General Practice for Clinical Trials Unit, Inala

  • Michael Crookes, MBBS · Peninsula Medical Centre

  • Alan James, MBBS · Sir Charles Gairdner Hospital

  • Phillip Thompson, MBBS · Mount Medical Centre

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
45 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-07-31
Completion
2006-08-31

Countries

  • Australia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00117182 on ClinicalTrials.gov