Dual Chamber Versus Single Chamber Cardiac Pacing in People 80 Years of Age and Older

Summary

Of the 19,000 pacemakers implanted across Canada in 2002, 1/3 of them were for patients 80 years and older. This is the fastest growing segment of our population, yet no study has specifically been done in this age group to determine the optimal pacing mode.

We wish to determine whether dual chamber or single chamber pacing is associated with a reduction in emergency room visits or hospitalizations for cardiovascular causes (e.g., congestive heart failure (CHF), atrial fibrillation (AF)) resulting in improved quality of life.

Conditions

• Atrial Fibrillation
• Cardiac Pacing, Artificial

Interventions

DEVICE

Dual chamber cardiac pacemaker

Physiologic pacemakers usually have two leads - one positioned in the right atrium (upper heart chamber) and one positioned in the right ventricle.

DEVICE

Single chamber cardiac pacemaker

Ventricular pacemakers have a single lead (wire) positioned in the right ventricle (lower pumping chamber) to sense and pace the ventricle.

Sponsors & Collaborators

• Calgary Health Trust

  collaborator OTHER

• University of Calgary

  lead OTHER

Principal Investigators

• Anne M Gillis, MD · Director of Pacing and Electrophysiology, Professor of Medicine, University of Calgary

• Derek V Exner, MD, MPH · University of Calgary

• D. George Wyse, MD, PhD · University of Calgary

• L. Brent Mitchell, MD · University of Calgary

• Robert S Sheldon, MD, Ph D · University of Calgary

• John M Rothschild, MD · University of Calgary

• Henry J Duff, MD · University of Calgary

• John Burgess, MD · University of Calgary

• Alexander Bayes, MD · University of Calgary

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2003-08-31

Primary Completion

2008-09-30

Completion

2009-11-30

Countries

• Canada

Study Locations