Study of the Tumor Saturation and Biological Activity of MEDI-522 (Abergrin) in Patients With Advanced Malignant Melanoma
NCT00111696 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2012-03-14
Summary
To describe the tumor tissue saturation by MEDI-522 in patients with advanced malignant melanoma.
Conditions
- Malignant Melanoma
Interventions
- BIOLOGICAL
-
MEDI-522
Supplied at a concentration of 50 mg/mL in both 2 mL and 10mL vials
Sponsors & Collaborators
-
MedImmune LLC
lead INDUSTRY
Principal Investigators
-
Stergios Moschos, MD · University of Pittsburgh
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-05-31
- Primary Completion
- 2007-08-31
- Completion
- 2007-11-30
Countries
- United States
Study Locations
More Related Trials
-
Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma
NCT00399113 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma
NCT01026051 ·Status: TERMINATED ·Phase: PHASE2
-
Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Melanoma
NCT00004184 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Immune Responses To Antigen-Bearing Dendritic Cells in Patients With Malignancy
NCT00700167 ·Status: COMPLETED ·Phase: PHASE1
-
Treatment of Metastatic Melanoma With Autologous Melan-A/MART-1 Specific CTL Clones
NCT00720031 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Monoclonal Antibody Therapy in Treating Patients With Advanced Solid Tumors
NCT00052403 ·Status: WITHDRAWN ·Phase: PHASE1
-
Study of CP-675,206 in Refractory Melanoma
NCT00254579 ·Status: COMPLETED ·Phase: PHASE2
-
Monoclonal Antibody Therapy in Treating Patients With Refractory Advanced Solid Tumors or Lymphoma
NCT00049712 ·Status: COMPLETED ·Phase: PHASE1
-
Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Melanoma or Brain Tumors
NCT00002754 ·Status: COMPLETED ·Phase: PHASE1
-
Local Treatment of Metastatic Melanoma With Autologous Lymphocytes and the Bispecific Antibody rM28
NCT00204594 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Modified Vaccine for High Risk or Low Residual Melanoma Patients
NCT01898039 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
The Anti-CTLA-4 Monoclonal Antibody Tremelimumab in Malignant Mesothelioma
NCT01655888 ·Status: UNKNOWN ·Phase: PHASE2
-
Monoclonal Antibody and Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Has Been Removed During Surgery
NCT00025181 ·Status: COMPLETED ·Phase: PHASE1
-
Immunotherapy of HLA-A2 Positive Stage III/IV Melanoma Patients
NCT00112229 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant Melanoma
NCT01211262 ·Status: COMPLETED ·Phase: PHASE1
-
Immunization of HLA-A201 Patients With Metastatic Melanoma Using a Combination of Immunodominant Peptides From Three Melanoma Antigens, MART-1, GP100 and Tyrosinase
NCT00001685 ·Status: COMPLETED ·Phase: PHASE2
-
(Bispecific) Antibodies in Cancer Patients
NCT05119257 ·Status: AVAILABLE
-
A Phase I Study of Intravenous Recombinant Human IL-15 in Adults With Refractory Metastatic Malignant Melanoma and Metastatic Renal Cell Cancer
NCT01021059 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC
NCT04995523 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Stage IV Cutaneous Melanoma
NCT00074230 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Melanoma
NCT07288203 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Immune Responses in Patients With Metastatic Melanoma
NCT01416844 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Study With ABL103 in Subjects With Advanced or Metastatic Solid Tumors
NCT06126666 ·Status: RECRUITING ·Phase: PHASE1
-
Immunotherapy of HLA-A2 Positive Stage II-IV Melanoma Patients
NCT01308294 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Peptide Vaccination for Patients at High Risk for Recurrent Melanoma
NCT00059475 ·Status: COMPLETED ·Phase: PHASE2