Mifepristone as Adjunctive Therapy in Alzheimer's Disease
NCT00105105 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 160
Last updated 2009-12-11
Summary
The purpose of this study is to evaluate the effects of C-1073 (Mifepristone) on cognition in patients with Alzheimer's disease (AD) who are also taking an acetylcholinesterase inhibitor (Aricept, Exelon or Reminyl).
Conditions
Interventions
- DRUG
Sponsors & Collaborators
-
Institute for the Study of Aging (ISOA)
collaborator OTHER -
Corcept Therapeutics
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-04-30
- Primary Completion
- 2005-11-30
- Completion
- 2005-11-30
Countries
- United States
Study Locations
More Related Trials
-
Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia
NCT00095719 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anti-Abeta (MABT5102A) in Patients With Alzheimer's Disease
NCT00736775 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's
NCT00105547 ·Status: COMPLETED ·Phase: PHASE3
-
Memory Impairment Study (Mild Cognitive Impairment Study)
NCT00000173 ·Status: COMPLETED ·Phase: PHASE3
-
The Use of Memantine for Prevention of Alzheimer's Disease
NCT05063851 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease
NCT00607308 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Long-term Safety of ABT-089 for Subjects With Mild-to-moderate Alzheimer's Disease Who Participated in the M06-876 Study
NCT00809510 ·Status: TERMINATED ·Phase: PHASE2
-
Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease
NCT03486938 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients With Mild to Moderate Alzheimer's Disease (AD)
NCT00104273 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease
NCT00096473 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety, Tolerability, and Blood Levels of ACU193 in Participants With MCI or Mild AD
NCT04931459 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Simvastatin in Amnestic Mild Cognitive Impairment (MCI) Patients
NCT00842920 ·Status: UNKNOWN ·Phase: PHASE4
-
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ABT-957 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors
NCT02220738 ·Status: TERMINATED ·Phase: PHASE1
-
A Brief Study To Evaluate The Safety, Tolerability, And Blood Levels Of Multiple Doses Of PF-044467943 Or Placebo In Combination With Donepezil In Subjects With Mild To Moderate Alzheimer's Disease
NCT00988598 ·Status: COMPLETED ·Phase: PHASE1
-
A Randomized, Placebo-Controlled Trial to Examine the Efficacy of Oral Donepezil in Subjects With MCI
NCT00483028 ·Status: COMPLETED ·Phase: NA
-
A Study of the Safety and Tolerability of ASP0777 in Subjects With Alzheimer's Disease (AD) Taking a Stable Dose of Donepezil
NCT01406145 ·Status: COMPLETED ·Phase: PHASE1
-
Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease
NCT00722046 ·Status: COMPLETED ·Phase: PHASE2
-
Memory Aid for Informed Consent in Alzheimer's Research
NCT00105612 ·Status: COMPLETED ·Phase: NA
-
Elpipodect (MK-8189) Safety and Tolerability in Participants With Alzheimer's Disease With or Without Symptoms of Agitation-Aggression and/or Psychosis (MK-8189-017)
NCT05227118 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Efficacy and Safety of GSK239512 in Alzheimer's Disease
NCT01009255 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008)
NCT06721156 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Rivastigmine Monotherapy and Combination Therapy With Memantine in Patients With Moderately Severe Alzheimer's Disease Who Failed to Benefit From Previous Cholinesterase Inhibitor Treatment
NCT00234637 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease
NCT05104463 ·Status: COMPLETED ·Phase: PHASE2
-
The Effect of Cognitive Function as Measured by Repeated Cognitive Measures After 12 Weeks Treatment With Donepezil
NCT01024660 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Phase I, Single IV Dose Of PF-04360365 In Adults With Mild To Moderate Alzheimer's Disease
NCT00455000 ·Status: COMPLETED ·Phase: PHASE1