NGR-TNF in Treating Patients With Advanced Solid Tumors
NCT00098943 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 70
Last updated 2012-09-24
Summary
RATIONALE: Targeted therapy with tumor necrosis factor combined with a fusion protein may stop the growth of solid tumors by stopping blood flow to the tumor.
PURPOSE: This phase I trial is studying the side effects and best dose of NGR-TNF in treating patients with advanced solid tumors.
Conditions
- Colorectal Cancer
- Head and Neck Cancer
- Kidney Cancer
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- BIOLOGICAL
-
CNGRC peptide-TNF alpha conjugate
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Principal Investigators
-
Cornelis J. A. Punt, MD, PhD · Universitair Medisch Centrum St. Radboud - Nijmegen
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-09-30
- Primary Completion
- 2007-11-30
Countries
- Germany
- Netherlands
Study Locations
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