Study of Interleukin-21 for Metastatic Malignant Melanoma and Metastatic Kidney Cancer
NCT00095108 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 43
Last updated 2009-03-09
Summary
This study is being done to see if an experimental drug called recombinant interleukin-21 (rIL-21) when given to patients with stage 4 malignant melanoma or stage 4 kidney cancer is safe and has any effect on these types of cancers.
Conditions
- Melanoma
- Kidney Neoplasms
- Metastases
Interventions
- DRUG
-
Recombinant Human Interleukin-21
Sponsors & Collaborators
-
ZymoGenetics
lead INDUSTRY
Principal Investigators
-
Diana Hausman, MD · ZymoGenetics
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-05-31
- Primary Completion
- 2007-01-31
- Completion
- 2007-01-31
Countries
- United States
Study Locations
More Related Trials
-
Interleukin-7 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
NCT00091338 ·Status: COMPLETED ·Phase: PHASE1
-
Trial of Outpatient Intravenous Interleukin-2 in Malignant Melanoma and Metastatic Kidney Cancer
NCT01355562 ·Status: WITHDRAWN ·Phase: PHASE2
-
Natural Killer Cell (CYNK-001) Infusions in Adults with AML
NCT04310592 ·Status: TERMINATED ·Phase: PHASE1
-
Interleukin-2 in Treating Patients With Metastatic Kidney Cancer
NCT00018941 ·Status: COMPLETED ·Phase: PHASE3
-
Vaccine Therapy in Treating Patients With Stage IV or Relapsed Malignant Melanoma
NCT00005617 ·Status: COMPLETED ·Phase: PHASE1
-
Biomed 101 and Interleukin-2 in Treating Patients With Kidney Cancer
NCT00004890 ·Status: COMPLETED ·Phase: PHASE1
-
Recombinant Interleukin-15 in Treating Patients With Advanced Melanoma, Kidney Cancer, Non-small Cell Lung Cancer, or Squamous Cell Head and Neck Cancer
NCT01727076 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy Followed by gp100 Lymphocytes and Aldesleukin to Treat Melanoma
NCT00665470 ·Status: COMPLETED ·Phase: PHASE2
-
Cultured White Cells Plus Interleukin-2 to Treat Advanced Kidney Cancer
NCT00091611 ·Status: TERMINATED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma
NCT00056134 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Interleukin-7 in Treating Patients With Metastatic Melanoma or Locally Advanced or Metastatic Kidney Cancer
NCT00492440 ·Status: TERMINATED ·Phase: PHASE1
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019448 ·Status: COMPLETED ·Phase: PHASE2
-
Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma
NCT00005949 ·Status: COMPLETED ·Phase: PHASE2
-
Low-dose Interleukin-2 and Pembrolizumab in Melanoma and Renal Cell Cancer
NCT03111901 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Peptide Vaccination for Patients at High Risk for Recurrent Melanoma
NCT00059475 ·Status: COMPLETED ·Phase: PHASE2
-
Biological Therapy in Treating Patients With Metastatic Cancer
NCT00002733 ·Status: COMPLETED ·Phase: PHASE2
-
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
NCT01993719 ·Status: COMPLETED ·Phase: PHASE2
-
Mechanism of Action of High-Dose IL-2 (Aldesleukin) in Metastatic Melanoma and Kidney Cancer
NCT00304460 ·Status: COMPLETED ·Phase: PHASE1
-
High-Dose Intravenous Interleukin-2 in Treating Patients With Metastatic Renal Cell Carcinoma (Kidney Cancer) That Has Not Responded to Previous Low-Dose Intravenous or Subcutaneous Interleukin-2
NCT00080977 ·Status: UNKNOWN ·Phase: PHASE2
-
Interleukin-2 and Sargramostim After Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma
NCT00085579 ·Status: WITHDRAWN ·Phase: PHASE2
-
Interleukin-12 and Interferon Alfa in Treating Patients With Metastatic Kidney Cancer or Malignant Melanoma
NCT00004244 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
NCT00019721 ·Status: COMPLETED ·Phase: PHASE2
-
Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma
NCT04309084 ·Status: UNKNOWN ·Phase: PHASE1
-
Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso
NCT02580747 ·Status: UNKNOWN ·Phase: PHASE1
-
Radiotherapy As an Immunological Booster in Patients with Metastatic Melanoma or Renal Cell Carcinoma Treated with High-dose Interleukin-2
NCT01884961 ·Status: COMPLETED ·Phase: PHASE2