Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso
NCT02580747 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2015-10-20
Summary
RATIONALE: Placing a tumor antigen chimeric receptor that has been created in the laboratory into patient autologous or donor-derived T cells may make the body build immune response to kill cancer cells.
PURPOSE: This clinical trial is studying genetically engineered lymphocyte therapy in treating patients with Relapsed and/or Chemotherapy Refractory Advanced Malignancies.
Conditions
- Malignant Mesothelioma
- Pancreatic Cancer
- Ovarian Tumor
- Triple Negative Breast Cancer
- Endometrial Cancer
- Other Mesothelin Positive Tumors
Interventions
- BIOLOGICAL
-
anti-meso-CAR vector transduced T cells
genetically engineered lymphocyte therapy
Sponsors & Collaborators
-
Chinese PLA General Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-10-31
- Primary Completion
- 2017-11-30
- Completion
- 2018-11-30
Countries
- China
Study Locations
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