Irinotecan and Flavopiridol in Treating Patients With Advanced Liver Cancer
NCT00087282 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-24
Summary
RATIONALE: Drugs used in chemotherapy, such as irinotecan and flavopiridol, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving irinotecan together with flavopiridol works in treating patients with advanced liver cancer.
Conditions
Interventions
- DRUG
-
alvocidib
- DRUG
-
irinotecan hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Ghassan Abou-Alfa, MD · Memorial Sloan Kettering Cancer Center
-
Gary K. Schwartz, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-06-30
- Completion
- 2006-07-31
Countries
- United States
Study Locations
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