Efficacy of Pegamotecan (PEG-Camptothecin) in Localized or Metastatic Cancer of the Stomach or Gastroesophageal Junction
NCT00080002 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2012-09-06
Summary
The purpose of this study is to evaluate the safety and efficacy of pegamotecan (PEG-camptothecin) in patients with pathologically-diagnosed locally advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction who have relapsed or progressed following one prior chemotherapy treatment regimen.
Conditions
- Cancer of Stomach
- Gastroesophageal Cancer
Interventions
- DRUG
-
Pegamotecan
Sponsors & Collaborators
-
Enzon Pharmaceuticals, Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-12-31
More Related Trials
-
Study With Cabazitaxel in Previously Treated Patients With Advanced or Metastatic Gastric Cancer
NCT01956149 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating the Efficacy and Safety With CAR-T for Stomach Cancer
NCT02725125 ·Status: UNKNOWN ·Phase: NA
-
Irinotecan in Treating Patients With Advanced Cancer of the Stomach
NCT00003137 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach
NCT00020761 ·Status: COMPLETED ·Phase: PHASE2
-
Savolitinib for Treating Gastric Cancer and Esophagogastric Junction Adenocarcinoma Patients
NCT04923932 ·Status: COMPLETED ·Phase: PHASE2
-
Radical Gastrectomy and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Locally Advanced Gastric Cancer
NCT02528110 ·Status: COMPLETED ·Phase: PHASE2
-
BGB A317 in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Carcinoma
NCT03469557 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers
NCT05296005 ·Status: WITHDRAWN ·Phase: PHASE1
-
Pharmacogenomically Selected Treatment for Gastric and Gastroesophageal Junction (GEJ) Tumors
NCT00515216 ·Status: COMPLETED ·Phase: PHASE2
-
Sequentially Administered CPT-11 and Mitomycin C in Patients With Advanced Esophageal and Stomach Cancer
NCT00201747 ·Status: COMPLETED ·Phase: PHASE2
-
First-Line Treatment for Locally Advanced or Metastatic Mesenchymal Epithelial Transition Factor (MET) - Positive Gastric, Lower Esophageal, or Gastroesophageal Junction (GEJ) Adenocarcinoma
NCT01697072 ·Status: TERMINATED ·Phase: PHASE3
-
Docetaxel and Capecitabine in Treating Patients With Metastatic Cancer of the Stomach or Gastroesophageal Junction
NCT00054457 ·Status: COMPLETED ·Phase: PHASE2
-
Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
NCT03092518 ·Status: COMPLETED ·Phase: PHASE2
-
huC242-DM4 Treating Patients With Metastatic Gastric or Gastroesophageal Junction Carcinomas
NCT00620607 ·Status: WITHDRAWN ·Phase: PHASE2
-
Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
NCT05702229 ·Status: RECRUITING ·Phase: PHASE2
-
Comparison of Combination Chemotherapy Regimens in Treating Patients With Advanced Stomach Cancer
NCT00003172 ·Status: COMPLETED ·Phase: PHASE2
-
Pre-operative Chemotherapy Plus Bevacizumab With Early Salvage Therapy Based on PET Assessment of Response in Patients With Locally Advanced But Resectable Gastric and GEJ Adenocarcinoma
NCT00737438 ·Status: COMPLETED ·Phase: PHASE2
-
Intraperitoneal Chemotherapy Guided by the Detection of DNA in Peritoneal Lavage Fluid in Patients With Gastric Cancer
NCT05497739 ·Status: UNKNOWN ·Phase: PHASE2
-
DX-8951f in Treating Patients With Metastatic Stomach Cancer
NCT00017212 ·Status: COMPLETED ·Phase: PHASE2
-
Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence
NCT07139951 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Intravenous Edotecarin in Patients With Advanced Gastric Cancer That Has Progressed or Recurred After Chemotherapy
NCT00087503 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/II Study of Paclitaxel Plus CPT-11 in Pts. With 2nd Line Chemotherapy of Inoperable or Recurrent GC.
NCT00209612 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
BMS-247550 in Treating Patients With Recurrent Metastatic Stomach Cancer That Has Been Previously Treated With Chemotherapy
NCT00017056 ·Status: COMPLETED ·Phase: PHASE2
-
Tesetaxel as Second-line Therapy for Patients With Advanced Gastric Cancer
NCT01095120 ·Status: UNKNOWN ·Phase: PHASE2
-
Saracatinib in Treating Patients With Locally Advanced or Metastatic Stomach or Gastroesophageal Junction Cancer
NCT00607594 ·Status: COMPLETED ·Phase: PHASE2