Celecoxib and Erlotinib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00072072 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2013-09-20
Summary
RATIONALE: Celecoxib may stop the growth of cancer by stopping blood flow to the tumor. Erlotinib and celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Combining celecoxib with erlotinib may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of celecoxib when given together with erlotinib in treating patients with stage IIIB or stage IV non-small cell lung cancer.
Conditions
Interventions
- DRUG
-
celecoxib
- DRUG
-
erlotinib hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Robert A. Figlin, MD, FACP · Jonsson Comprehensive Cancer Center
-
Karen Rickard · City of Hope Comprehensive Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-08-31
- Completion
- 2006-01-31
Countries
- United States
Study Locations
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