MedTrace Logo

Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

NCT00062231 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 351

Last updated 2012-09-24

No results posted yet for this study

Summary

RATIONALE: Antibiotics such as amoxicillin, ciprofloxacin, and moxifloxacin may be effective in preventing or controlling fever and neutropenia in patients with cancer. It is not yet known whether moxifloxacin alone is more effective than amoxicillin combined with ciprofloxacin in treating neutropenia and fever.

PURPOSE: This randomized clinical trial is studying how well moxifloxacin works and compares it to ciprofloxacin together with amoxicillin in treating neutropenia and fever in patients with cancer.

Conditions

Interventions

DRUG

amoxicillin-clavulanate potassium

DRUG

ciprofloxacin

DRUG

moxifloxacin hydrochloride

PROCEDURE

management of therapy complications

Sponsors & Collaborators

  • European Organisation for Research and Treatment of Cancer - EORTC

    lead NETWORK

Principal Investigators

  • Winfried Kern, MD · University Hospital Freiburg

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-04-30
Primary Completion
2006-10-31

Countries

  • Belgium
  • France
  • Germany
  • Israel
  • Italy
  • Slovakia
  • Switzerland
  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00062231 on ClinicalTrials.gov