Perifosine in Treating Patients With Metastatic or Recurrent Malignant Melanoma
NCT00053781 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2023-08-04
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of perifosine in treating patients who have metastatic or recurrent malignant melanoma.
Conditions
- Melanoma (Skin)
Interventions
- DRUG
-
perifosine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
NCIC Clinical Trials Group
lead NETWORK
Principal Investigators
-
Donald S. Ernst, MD, FRCPC · London Health Sciences Centre
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-06-20
- Primary Completion
- 2004-09-14
- Completion
- 2009-12-21
- FDA Drug
- Yes
Countries
- Canada
Study Locations
More Related Trials
-
CY503 for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy
NCT00658437 ·Status: COMPLETED ·Phase: PHASE2
-
Flavopiridol in Treating Patients With Metastatic Malignant Melanoma
NCT00005971 ·Status: COMPLETED ·Phase: PHASE2
-
Tipifarnib in Treating Patients With Metastatic Malignant Melanoma
NCT00060125 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial Of ZK-EPO (ZK 219477) (Sagopilone) In Metastatic Melanoma
NCT00598507 ·Status: COMPLETED ·Phase: PHASE2
-
Fotemustine in Treating Patients With Metastatic Melanoma
NCT00560118 ·Status: TERMINATED ·Phase: PHASE2
-
High-Dose Interferon Alfa in Treating Patients With Stage II or StageIII Melanoma
NCT00447356 ·Status: WITHDRAWN ·Phase: PHASE3
-
PEG-Interferon Alfa-2b in Treating Patients With Stage IV Melanoma
NCT00049530 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Interferon Alfa in Treating Patients With Stage III or Stage IV Melanoma
NCT00027742 ·Status: COMPLETED ·Phase: PHASE2
-
Pazopanib Hydrochloride in Treating Patients With Metastatic Melanoma That Cannot be Removed by Surgery
NCT00861913 ·Status: COMPLETED ·Phase: PHASE2
-
Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma
NCT02500576 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Compare the Efficacy and Safety of CC-5013 vs. Placebo in Subjects With Metastatic Malignant Melanoma.
NCT00057616 ·Status: COMPLETED ·Phase: PHASE3
-
Fotemustine and Dacarbazine Versus Dacarbazine +/- Alpha Interferon in Advanced Malignant Melanoma
NCT01359956 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors
NCT06799533 ·Status: TERMINATED ·Phase: PHASE1
-
Chemotherapy Followed by Infusion of DMF5 Cells to Treat Metastatic Melanoma
NCT00924001 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma
NCT00243061 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study of UCN-01 in Metastatic Melanoma
NCT00072189 ·Status: TERMINATED ·Phase: PHASE2
-
S0008: Chemotherapy Plus Biological Therapy in Treating Patients With Melanoma
NCT00006237 ·Status: COMPLETED ·Phase: PHASE3
-
O6-benzylguanine and Carmustine in Treating Patients With Unresectable Locally Recurrent or Metastatic Melanoma
NCT00005961 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma
NCT00003027 ·Status: COMPLETED ·Phase: PHASE3
-
Parallel Phase I/II Trial of Decitabine and Peg-Interferon in Melanoma: Phase I Portion
NCT00791271 ·Status: TERMINATED ·Phase: PHASE1
-
A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma
NCT04657991 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors
NCT05571839 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma
NCT00185302 ·Status: COMPLETED ·Phase: PHASE2
-
Viral Therapy in Treating Patients With Metastatic Melanoma
NCT00651157 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy Study Of P276-00 In Subjects Of Malignant Melanoma Positive For Cyclin D1 Expression
NCT00835419 ·Status: COMPLETED ·Phase: PHASE2