Flavopiridol in Treating Patients With Metastatic Malignant Melanoma
NCT00005971 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 17
Last updated 2020-04-09
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of flavopiridol in treating patients who have metastatic malignant melanoma.
Conditions
- Melanoma (Skin)
Interventions
- DRUG
-
alvocidib
Sponsors & Collaborators
-
NCIC Clinical Trials Group
lead NETWORK
Principal Investigators
-
Susan Burdette-Radoux, MD · McGill Cancer Centre at McGill University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-07-04
- Primary Completion
- 2001-08-24
- Completion
- 2009-12-21
- FDA Drug
- Yes
Countries
- Canada
Study Locations
More Related Trials
-
Study to Compare the Efficacy and Safety of CC-5013 vs. Placebo in Subjects With Metastatic Malignant Melanoma.
NCT00057616 ·Status: COMPLETED ·Phase: PHASE3
-
AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma
NCT00243061 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Temozolomide in Treating Patients With Unresectable or Metastatic Melanoma
NCT00003747 ·Status: UNKNOWN ·Phase: PHASE1
-
SB-715992 in Treating Patients With Metastatic or Recurrent Malignant Melanoma
NCT00095953 ·Status: COMPLETED ·Phase: PHASE2
-
Melanoma Treatment With White Blood Cells That Destroy MART Expressing Tumor Cells
NCT01495572 ·Status: TERMINATED ·Phase: PHASE2
-
Tipifarnib in Treating Patients With Metastatic Malignant Melanoma
NCT00060125 ·Status: COMPLETED ·Phase: PHASE2
-
CP-461 in the Treatment of Patients With Advanced Melanoma
NCT00060710 ·Status: TERMINATED ·Phase: PHASE2
-
Fluzoparib in Combination With Camrelizumab and Temozolomide in Advanced Melanoma
NCT05983237 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma
NCT00314106 ·Status: COMPLETED ·Phase: PHASE2
-
Intravital Microscopy in Identifying Tumor Vessels in Patients With Stage IB-IIIC Melanoma Undergoing Sentinel Lymph Node Biopsy
NCT02857374 ·Status: COMPLETED ·Phase: NA
-
Fecal Microbial Transplantation in Combination With Immunotherapy in Melanoma Patients (MIMic)
NCT03772899 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma
NCT04165967 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy Followed by Infusion of DMF5 Cells to Treat Metastatic Melanoma
NCT00924001 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Mirdametinib in Patients With Advanced NF1-mutant Melanoma
NCT07237100 ·Status: RECRUITING ·Phase: PHASE2
-
Study of First-line Treatment Patterns and Clinical Outcomes in Patients With Advanced Melanoma in the United Kingdom
NCT03448497 ·Status: COMPLETED
-
Radiation and Combination Immunotherapy for Melanoma
NCT03850691 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab Combined With Ipilimumab Followed by Nivolumab Monotherapy as First-Line Treatment for Patients With Advanced Melanoma
NCT02599402 ·Status: COMPLETED ·Phase: PHASE3
-
RAD001 Plus Bevacizumab in Metastatic Melanoma
NCT00591734 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma
NCT06961357 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
FHD-286 in Subjects With Metastatic Uveal Melanoma
NCT04879017 ·Status: TERMINATED ·Phase: PHASE1
-
Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma
NCT00590824 ·Status: COMPLETED ·Phase: PHASE2
-
Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma
NCT03646617 ·Status: RECRUITING ·Phase: PHASE2
-
Individualized Treatments in Adults With Relapsed/Refractory Cancers
NCT06024603 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Panobinostat (LBH589) in Patients With Metastatic Melanoma
NCT01065467 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of Palbociclib in Advanced Acral Melanoma With Cell Cycle Gene Aberrations
NCT03454919 ·Status: UNKNOWN ·Phase: PHASE2