Nasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity
NCT00041821 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64
Last updated 2006-03-23
Summary
This study seeks to document differences in nasal irritant sensitivity within the population. The investigators are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant sensitivity. This is important in understanding symptom reporting patterns in air pollution situations (particularly in so-called "problem buildings"), as well as in understanding the reflex mechanism of a response of the nose to irritants (e.g., nasal congestion).
Conditions
- Rhinitis, Allergic, Nonseasonal
Interventions
- PROCEDURE
-
Nasal irritation thresholds and irritant provocation
Sponsors & Collaborators
-
National Institute of Environmental Health Sciences (NIEHS)
lead NIH
Study Design
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 69 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2000-09-30
Countries
- United States
Study Locations
More Related Trials
-
Innate Neutrophilic Nasal Inflammation in a Pollen Exposure Chamber
NCT03496103 ·Status: COMPLETED ·Phase: PHASE1
-
Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls
NCT01862523 ·Status: COMPLETED ·Phase: PHASE4
-
A Study in Subjects With Perennial Allergic Rhinitis
NCT00210015 ·Status: COMPLETED ·Phase: PHASE2
-
Nasal Allergen Challenge in Rhinitic Subjects
NCT01286129 ·Status: COMPLETED ·Phase: NA
-
Evaluation of the Efficacy of Allergen-specific Immunotherapy Using Assessment in an Allergen Exposure chamber-a Randomized Placebo-controlled Double-blind Study
NCT06778213 ·Status: RECRUITING ·Phase: PHASE4
-
Evaluation of Nasal Inflammatory Biomarkers
NCT03450031 ·Status: COMPLETED ·Phase: NA
-
Validation of a Combined Symptom and Medication Score in Patients Suffering From Allergic Rhinoconjunctivitis
NCT04071249 ·Status: COMPLETED
-
The Effect of Allergen Immunotherapy on Exhaled Nitric Oxide in Adult Patients With Asthma and Allergic Rhinitis
NCT01318954 ·Status: COMPLETED
-
Study Of Perennial Allergic Rhinitis
NCT00358475 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluating the Need for New Rhinitis Treatment
NCT01875276 ·Status: COMPLETED
-
Sensitivity and Specificity of Nasal Provocation Test in Allergic Rhinitis to House Dust Mites
NCT01485523 ·Status: COMPLETED
-
Concomitant Intranasal Antihistamine and Corticosteroid in Stepwise Treatment Strategy for Allergic Rhinitis
NCT05708157 ·Status: UNKNOWN
-
Effect of a Nasal Bolus Allergen Challenge on Inflammatory Markers
NCT00483353 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluation of Nasal Mucosal Permeability in Controls and House Dust Mite Allergic Rhinitis Patients
NCT02461797 ·Status: COMPLETED ·Phase: NA
-
App Based Study on the Symptoms of Patients With Allergic Rhinitis in the Pollen Season
NCT03112252 ·Status: COMPLETED
-
Biomarkers in Nasal Samples of Seasonal Allergic Rhinitics
NCT04670627 ·Status: COMPLETED
-
Study of Bronchodilation Effects of Cetirizine
NCT01781507 ·Status: COMPLETED ·Phase: PHASE4
-
the Relationship Between Allergic Rhinitis and the Risk of Symptom in Patients With Mild COVID-19
NCT05753241 ·Status: COMPLETED
-
The Effect of Nasal Carbon Dioxide (CO2) in the Treatment of Seasonal Allergic Rhinitis
NCT00688441 ·Status: COMPLETED ·Phase: PHASE2
-
Study To Evaluate Patient Preference, Satisfaction And Efficacy Of a Nasal Aerosol Versus an Aqueous Nasal Spray
NCT01401465 ·Status: COMPLETED ·Phase: PHASE3
-
Compare Captisol-Enabled (CE) Budesonide + Azelastine Nasal Solution and Rhinocort Aqua + Astelin in an Environmental Exposure Chamber (EEC) Study of Allergic Rhinitis
NCT00940953 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of a Novel Questionnaire to Assess Patient Satisfaction With and Preference of Intranasal Corticosteroids for the Treatment of Allergic Rhinitis
NCT01287364 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Trial to Elaborate a Cutaneous Antigen Neutralization Test in Patients Suffering From Rhinoconjunctivitis
NCT00461721 ·Status: COMPLETED
-
The Effect of Nasal Carbon Dioxide (CO2) on Nasal Congestion in Subjects With Perennial Allergic Rhinitis
NCT00638755 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of House Dust Mite Allergen Extract in the Treatment of Allergic Rhinoconjunctivitis
NCT00263549 ·Status: COMPLETED ·Phase: PHASE4