Prevention of Dichloroacetate Toxicity
NCT00031161 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2015-03-25
Summary
This is a study to determine the safety of dichloroacetate (DCA) with a low-tyrosine diet given with or without nitisinone (NTBC) in children with chronic lactic acidosis (CLA).
Conditions
- Acidosis, Lactic
- Chronic Disease
Interventions
- DRUG
-
Nitisinone (NTBC)
- DRUG
-
Dichloroacetate
- BEHAVIORAL
-
Low-tyrosin diet
Sponsors & Collaborators
-
University of Florida
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- DOUBLE
Eligibility
- Min Age
- 3 Months
- Max Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-09-30
- Completion
- 2005-09-30
Countries
- United States
Study Locations
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