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Breast-Conserving Therapy Compared With Mastectomy Followed By Radiation Therapy in Treating Women With Locally Advanced Breast Cancer Previously Treated With Chemotherapy

NCT00028704 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2012-07-18

No results posted yet for this study

Summary

RATIONALE: Breast-conserving treatments such as radiation therapy or limited surgery are less invasive than mastectomy and may improve the quality of life. It is not yet known if breast-conserving treatments are as effective as mastectomy followed by radiation therapy in treating locally advanced breast cancer.

PURPOSE: Randomized phase III trial to compare the effectiveness of breast-conserving therapy with mastectomy followed by radiation therapy in treating women who have locally advanced breast cancer that has been previously treated with chemotherapy.

Conditions

Interventions

PROCEDURE

conventional surgery

RADIATION

radiation therapy

Sponsors & Collaborators

  • Central and Eastern European Oncology Group

    collaborator OTHER

  • Grupo Oncologico Cooperativo Chileno de Investigation

    collaborator NETWORK

  • International Collaborative Cancer Group

    collaborator OTHER

  • European Organisation for Research and Treatment of Cancer - EORTC

    lead NETWORK

Principal Investigators

  • Jacek Jassem, MD, PhD · Medical University of Gdansk

  • G. van Tienhoven, MD, PhD · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

  • Marzena Welnicka-Jaskiewicz, MD · Medical University of Gdansk

  • Rodrigo Arriagada, MD · Instituto de Radiomedicina

  • Marie Emson, BSc · International Collaborative Cancer Group

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-10-31
Primary Completion
2003-12-31

Countries

  • Belgium
  • Chile
  • Israel
  • Netherlands
  • Poland
  • Portugal
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00028704 on ClinicalTrials.gov