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Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder

NCT00025935 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2350

Last updated 2026-05-22

No results posted yet for this study

Summary

This study seeks to learn more about the symptoms of severe mood dysregulation in children and adolescents ages 7-17. Children and adolescents with severe mood dysregulation (SMD) display chronic anger, sadness, or irritability, as well as hyperarousal (such as insomnia, distractibility, hyperactivity) and extreme responses to frustration (such as frequent, severe temper tantrums). Researchers will describe the moods and behaviors of children with these symptoms and use specialized testing and brain imaging to learn about the brain changes associated with this disorder.

Conditions

  • Mood Disorder

Interventions

DRUG

Lithium

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    lead NIH

Principal Investigators

  • Melissa A Brotman, Ph.D. · National Institute of Mental Health (NIMH)

Eligibility

Min Age
7 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-01-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00025935 on ClinicalTrials.gov