Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer
NCT00022594 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2012-07-24
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of liposomal lurtotecan in treating patients who have metastatic or locally recurrent head and neck cancer.
Conditions
Interventions
- DRUG
-
liposomal lurtotecan
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Principal Investigators
-
Florence Duffaud, MD · CHU de la Timone
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-05-31
- Primary Completion
- 2002-08-31
Countries
- Austria
- Belgium
- France
- Germany
- Italy
- Netherlands
- Portugal
- Spain
- Switzerland
- United Kingdom
Study Locations
More Related Trials
-
Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck
NCT01064479 ·Status: COMPLETED ·Phase: PHASE2
-
SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
NCT00095628 ·Status: COMPLETED ·Phase: PHASE2
-
Akt Inhibitor MK2206 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
NCT01349933 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Paclitaxel in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer
NCT00003206 ·Status: COMPLETED ·Phase: PHASE2
-
Combined Amivantamab, Carboplatin and Paclitaxel in Unresectable Locally Recurrent or Metastatic Head and Neck Cancer
NCT07062354 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Recurrent or Refractory Head and Neck Cancer
NCT00003327 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study of MEHD7945A Versus Cetuximab in Patients With Recurrent/Metastatic Squamous Cell Carcinoma of The Head And Neck
NCT01577173 ·Status: COMPLETED ·Phase: PHASE2
-
Trilaciclib in Preventing Hematopoietic Suppression in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
NCT06714266 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Fenretinide in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
NCT00006471 ·Status: COMPLETED ·Phase: PHASE2
-
Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers
NCT04747054 ·Status: RECRUITING ·Phase: PHASE3
-
Sorafenib in Combination With Carboplatin and Paclitaxel in Treating Participants With Metastatic or Recurrent Head and Neck Squamous Cell Cancer
NCT00494182 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Open-Label Trial Of Oral PF-00299804 By Continuous Dosing In Patients With Recurrent Or Metastatic Head And Neck Squamous Cell Cancer
NCT00768664 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer
NCT01316757 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Recurrent/Metastatic Head and Neck Cancers
NCT04902027 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Activity of BAY 43-9006 in Patients With Recurrent and/or Metastatic Head and Neck Cancer
NCT00199160 ·Status: COMPLETED ·Phase: PHASE2
-
NBTXR3, Radiation Therapy, and Pembrolizumab for the Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Cancer
NCT04862455 ·Status: TERMINATED ·Phase: PHASE2
-
Bryostatin 1 in Treating Patients With Metastatic or Recurrent Head and Neck Cancer
NCT00003443 ·Status: COMPLETED ·Phase: PHASE2
-
Re-irradiation With NBTXR3 in Combination With Pembrolizumab for the Treatment of Inoperable Locoregional Recurrent Head and Neck Squamous Cell Cancer
NCT04834349 ·Status: WITHDRAWN ·Phase: PHASE2
-
Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC
NCT04470024 ·Status: RECRUITING ·Phase: PHASE1
-
Phase II Trial Evaluating Axitinib In Patients With Unresectable, Recurrent Or Metastatic Head And Neck Cancer
NCT01469546 ·Status: COMPLETED ·Phase: PHASE2
-
Expansion Trial for Axitinib In Head And Neck Cancer
NCT02762513 ·Status: COMPLETED ·Phase: PHASE2
-
LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy
NCT01345682 ·Status: COMPLETED ·Phase: PHASE3
-
Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer
NCT01267240 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck
NCT04665843 ·Status: COMPLETED ·Phase: PHASE2
-
Weekly Carboplatin, Paclitaxel and Cetuximab Treatment for Patients With Recurrent or Metastatic SCCHN
NCT02124707 ·Status: COMPLETED ·Phase: PHASE2