Combination Chemotherapy in Treating Patients Who Have Advanced Solid Tumors
NCT00020488 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2015-04-30
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy in treating patients who have advanced solid tumors.
Conditions
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
FOLFIRI regimen
- DRUG
- DRUG
-
irinotecan hydrochloride
- DRUG
-
leucovorin calcium
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Eva Szabo, MD · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-02-28
Countries
- United States
Study Locations
More Related Trials
-
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
NCT00654160 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
NCT00003594 ·Status: COMPLETED ·Phase: PHASE3
-
UCN-01, Fluorouracil, and Leucovorin in Treating Patients With Metastatic or Unresectable Solid Tumors
NCT00042861 ·Status: COMPLETED ·Phase: PHASE1
-
Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin
NCT00004005 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Metastatic or Recurrent Cancer of the Stomach or Esophagus
NCT00005607 ·Status: UNKNOWN ·Phase: PHASE2
-
Alvocidib, Oxaliplatin, Fluorouracil, and Leucovorin Calcium in Treating Patients With Advanced Solid Tumors
NCT00080990 ·Status: COMPLETED ·Phase: PHASE1
-
Fluorouracil Plus UCN-01 in Treating Patients With Advanced or Refractory Solid Tumors
NCT00004059 ·Status: COMPLETED ·Phase: PHASE1
-
Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00004885 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Advanced Cancer That is Metastatic or Cannot Be Removed By Surgery
NCT00043121 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of Weekly Gemcitabine in Combination With Infusional Fluorodeoxyuridine and Oral Calcium Leucovorin in Adult Cancer Patients
NCT00001449 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas
NCT00019513 ·Status: COMPLETED ·Phase: PHASE1
-
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
NCT04205968 ·Status: RECRUITING ·Phase: PHASE2
-
Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI
NCT02833753 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
NCT00004102 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Unresectable Metastatic Colorectal Cancer
NCT00008060 ·Status: COMPLETED ·Phase: PHASE3
-
Chemotherapy With Raltitrexed and Fluorouracil in Treating Patients With Advanced Colorectal Cancer
NCT00002828 ·Status: COMPLETED ·Phase: PHASE1
-
Fluorouracil Plus Leucovorin With or Without Oxaliplatin in Treating Patients With Stage II or Stage III Colon Cancer
NCT00004931 ·Status: COMPLETED ·Phase: PHASE3
-
Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies
NCT01643499 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy With or Without SU5416 in Treating Patients With Metastatic Colorectal Cancer
NCT00021281 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal Cancer
NCT00006015 ·Status: TERMINATED ·Phase: PHASE2
-
Irinotecan, Fluorouracil, Leucovorin, and Oxaliplatin as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer
NCT00080951 ·Status: COMPLETED ·Phase: PHASE2
-
Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer
NCT02333188 ·Status: COMPLETED ·Phase: PHASE1
-
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
NCT05677490 ·Status: RECRUITING ·Phase: PHASE3
-
Comparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer
NCT00008281 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy and Radiation Therapy in Treating Patients With Colorectal Cancer
NCT00002801 ·Status: COMPLETED ·Phase: PHASE1