UCN-01 and Fludarabine in Treating Patients With Recurrent or Refractory Lymphoma or Leukemia
NCT00019838 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2015-04-29
Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining UCN-01 with chemotherapy may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of fludarabine when given with UCN-01 in treating patients with recurrent or refractory low-grade lymphoma or leukemia.
Conditions
Interventions
- DRUG
-
7-hydroxystaurosporine
- DRUG
-
fludarabine phosphate
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Wyndham H. Wilson, MD, PhD · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-07-31
Countries
- United States
Study Locations
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