Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases
NCT00019786 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 67
Last updated 2012-03-23
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving drugs in different ways may kill more tumor cells.
PURPOSE: This phase II trial is studying how well isolated hepatic perfusion with melphalan works in treating patients with primary unresectable liver cancer or liver metastases.
Conditions
- Colorectal Cancer
- Islet Cell Tumor
- Liver Cancer
- Metastatic Cancer
- Neuroendocrine Carcinoma
Interventions
- DRUG
-
isolated perfusion
- DRUG
-
melphalan
- PROCEDURE
-
conventional surgery
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
National Institutes of Health Clinical Center (CC)
lead NIH
Principal Investigators
-
H. Richard Alexander, MD, FACS · NCI - Surgery Branch
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-08-31
- Completion
- 2006-01-31
Countries
- United States
Study Locations
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